Lactic acid bacteria engage a hybrid metabolism which blends features of fermentation and respiration when they perform extracellular electron transfer.

Reducing Akt-mediated huntingtin phosphorylation decreases APP accumulation at the synapse by reducing its anterograde axonal transport and ameliorates learning and memory in a mouse model of familial Alzheimer disease.

Theoretical predictions and experiments on multicellular aggregates indicate that the extracellular matrix acts as a mechanical sensor, which regulates cell proliferation and migration in a three-dimensional environment.

FIB-SEM is used to identify comprehensively and reconstruct 192 neurons and their complete connectome for glomerulus VA1v of the Drosophila antennal lobe, in particular to reconstruct its local interneurons.

Direct in-vivo measurements in the human brain test validity of detailed computational models of trancranial electric stimulation and show that electric fields in the brain are weaker than currently assumed.

The combination of high-speed light sheet microscopy and suitable data analysis facilitates cell-accurate measurements across entire organs and opens the way to systematic, scale-bridging, in vivo studies of organogenesis.

The Drosophila lateral horn, a higher olfactory brain area, contains >165 genetically defined cell types with stereotyped odour responses across animals and improved odor categorisation compared with their inputs.

In vivo crosslinking approaches revealed that the edge-strand of Escherichia coli metallopeptidase BepA interacts with an assembly intermediate of β-barrel outer membrane protein LptD on the outer membrane protein translocon for its targeting to degradation or maturation.

Electrical and biomechanical stimuli directly bias cortical signal transduction and cytoskeletal waves, and the direct bias induced by an electric field develops slowly compared to the rapid surface-receptor-mediated response to chemotactic gradients.

Delivering specific patterns of electrical activity to the median nerve of the arm triggers reliable sensations of texture, suggesting that it may ultimately be possible to restore complex tactile information to users of prosthetic limbs.