Despite size heterogeneity, an epitope-resurfaced mature-form dengue VLP has the potential to induce quaternary structure-recognizing broad cross-reactive neutralizing antibodies.

The structure and composition of the elusive vertex complex in Tectiviridae is finally revealed and the newly reported protein conformations help to maintain the capsid architecture.

Water molecules and amino-acid side chain rotamers have been resolved in the cryoEM structure of T20S proteasome at 2.8 angstroms.

Diverse K_ATP channel inhibitors occupy a common binding pocket and stabilize an interaction between Kir6.2 and SUR1 to allosterically control gating and promote the assembly and trafficking of nascent channels.

The high-resolution structure of a filamentous flexible plant virus shows that there is structural homology between its coat protein and the nucleoproteins of an unrelated group of enveloped RNA animal viruses.

Fiducial-less tomography on single particle cryoEM samples reveals that most particles are adsorbed to the air-water interface and allows for researchers to diagnose and solve sample, grid, ice thickness, collection, and processing issues.

A combination of high-resolution structure determination, electrophysiology, and MD simulations reveal fundamental insight into the molecular function of voltage-gated chloride channels.

Electron cryo-microscopy has been used to determine the structure of Chikungunya virus-like particles and to provide new insights into their interactions with four different antibodies.

A protein-bounded organelle-like compartment from Synechococcus elongatus PCC 7942 is upregulated under sulfur starvation and contains a cysteine desulfurase cargo enzyme.

Nucleosome recognition by the SWR1C chromatin remodeling enzyme requires both nucleosomal acidic patches.