Neurite geometry enables expansive and highly-branched neuronal structures to operate like single electrical compartments and simple linear integrators.
A disinhibitory motif in the retina mediates noise resilience of motion detection using an inverted algorithm of disinhibition due to the interplay between network activity and synaptic plasticity.
A large interneuron in the Drosophila mushroom body has compartmentalized activity, which causes localized inhibition and predicts that Kenyon cells inhibit themselves more than they inhibit other individual Kenyon cells.
Feedback sensing of the intracellular calcium concentration suffices to reproduce the diversity of ionic conductances underlying normal cardiac electromechanical function in a genetically diverse population of mice.
Excitatory synapses that occur further away from the postsynaptic cell soma exhibit greater neurotransmitter release probability, which appears to improve signal transfer fidelity for high-frequency afferent firing.
Active dendritic processing enables an individual neuron to discriminate the spatial pattern of synaptic inputs, increasing neural and behavioral selectivity for escaping an impending threat.
Experimental and computational models reveal how parallel 'core' mechanisms shape direction selectivity at the dendrites of starburst amacrine cells and ganglion cells in the mouse retina.
