Par-complex-dependent cell polarity can be cell-autonomously conferred to non-polar Drosophila S2 cells, unveiling temporal patterns toward the cortical localization of Par-complex aggregates that include a meshwork containing unit segments.
Synaptophysins and gyrins dampen synaptic strength selectively at low frequencies, hinting that synaptic transmission may play a frequency filtering role in biological computation that is more general than currently envisioned.
Analysis of the atypical tryptophan biosynthetic operon of Chlamydia trachomatis revealed the simultaneous regulation of transcriptional initiation and termination by an iron-dependent repressor, expanding known regulatory mechanisms of this pathway.
A direct relationship between pupil diameter and electrophysiological correlates of attention, sensory stimulus processing and target detection was observed demonstrating that arousal has a substantial influence on perceptual decision-making.
Leave-One-Trial-Out (LOTO) is a general, efficient and easily implementable approach for inferring trial-by-trial measures of computational model parameters in order to link these measures to neural mechanisms.
Phototrophic growth laws are elucidated by combining computational modeling and experiments for quantitative evaluation of cellular physiology, morphology and proteome allocation across a wide range of light conditions.
In the context of an organism's ecology, physiology, and macroevolutionary history, inheritance and gene loss can yield emergent patterns of trait variability that give the appearance of gene acquisition.
Decision-makers are able to intentionally control neural excitability to strategically bias sensory evidence accumulation towards the decision bound that maximizes reward within a given ecological context.