Environmental gradients can modify a fundamental relationship between host community structure and disease, with implications for predicting disease risk in a changing world.

Transient Ca elevations of cytoplasmic calcium in cardiac myocytes profoundly activate cardiac Na/K pump activity in parallel with physical-chemical changes of the sarcolemma but without involvement of conventional signaling mechanisms.

Cooperation enables burying beetles to outcompete flies and adapt to a wider range of temperatures as thermal generalists.

While flooding events may drive spillover transmission of Leptospira spp. through dispersal of the bacteria at low elevations, at higher elevations environmental risk is more localised and directly driven by the distribution of local rat reservoir populations.

After myocardial infarction, gut microbiota affects platelet aggregation rate by regulating the absorption and metabolism of ticagrelor.

An integrative approach allows investigations of the relationship between an initial plasticity and the subsequent adaptive evolution during rapid adaptive modification of complex systems in the wild.

By integrating theoretical and empirical approaches, the results show that linking abiotic factor and biotic interactions on the niche width will be critical for understanding species-specific responses to climate change.

A novel neuroprotective pathway that enhances acetyl-CoA metabolism via inhibition of acetyl-CoA carboxylase 1 may prevent the contribution of the aging process in the brain to Alzheimer's disease.

The putative substrate pantoate binds to a sodium-coupled secondary transporter of the bile acid sodium symporter family, with sodium-dependent binding and conformational changes consistent with an elevator mechanism of transport.

Ultrasound promotes release of extracellular vesicles from cultured myotubes and elicits anti-inflammatory effects on macrophages, indicating the potential of ultrasound stimulation to muscle for anti-inflammatory purposes.