Kimberly M Fornace, Neal Alexander ... Chris Drakeley
Local human movement into mosquito habitats around forest edges intensifies interactions between pathogens, insects and people, increasing exposure risks to the zoonotic malaria Plasmodium knowlesi in Malaysian Borneo.
Mutants of influenza A virus with increased CpG dinucleotide frequencies show restricted replication and reduced or absent pathogenicity, and powerful host innate and adaptive responses to infection that confer immunity to re-infection.
Chaitanya A Kulkarni, Sergiy M Nadtochiy ... Paul S Brookes
Multi-omics reveals that Alkb homolog 7 (ALKBH7), α mitochondrial alpha-ketoglutarate dioxygenase of unclear function, regulates glyoxal metabolism, which may explain its role in necrosis and heart attack.
Gabriela C Olivera, Emily C Ross ... Antonio Barragan
The invasion of Toxoplasma to the CNS across cortical capillaries is restricted by the integrity of the blood-brain barrier (BBB) and exacerbated by the inflammatory response.
Daniel B Dorman, Joanna Jędrzejewska-Szmek, Kim T Blackwell
Inhibition enhances the spatial specificity of high calcium influx for cooperatively stimulated synapses, suggesting that inhibitory inputs may regulate both synapse-specific and heterosynaptic plasticity to support learning and memory.
Tom WN Walker, Konstantin Gavazov ... Jake M Alexander
Uphill migrations of lowland plants into warming alpine ecosystems may yield a positive climate feedback by accelerating soil microbial respiration and decreasing soil carbon content.