Browse the search results

Page 2 of 49
    1. Chromosomes and Gene Expression

    Conversion of random X-inactivation to imprinted X-inactivation by maternal PRC2

    Clair Harris et al.
    The PRC2 Polycomb complex made in the mouse oocyte prevents transcriptional inactivation of the maternal X-chromosome in the early embryo.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst

    Jan J Zylicz et al.
    Loss of a maternally inherited epigenetic modifier leads to establishment of an aberrant regulatory network in preimplantation embryos, developmental delay and destabilisation of cell-fate choices.
    1. Developmental Biology
    2. Evolutionary Biology

    The mlpt/Ubr3/Svb module comprises an ancient developmental switch for embryonic patterning

    Suparna Ray et al.
    mille-pattes micropeptides have conserved function in insect embryonic patterning together with transcription factor Shaven-baby and ubiquitin ligase Ubr3, except in flies wherein restoring broad embryonic Svb expression restores patterning potency.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    mRNA poly(A)-tail changes specified by deadenylation broadly reshape translation in Drosophila oocytes and early embryos

    Stephen W Eichhorn et al.
    Profiling of mRNA poly(A)-tail lengths and translational efficiencies provides new insights into posttranscriptional gene regulation in early Drosophila development.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Competition between histone and transcription factor binding regulates the onset of transcription in zebrafish embryos

    Shai R Joseph et al.
    The relative levels of histones and transcription factors in the nucleus determine transcriptional output in zebrafish embryos.
    1. Developmental Biology
    2. Genetics and Genomics

    A high-resolution mRNA expression time course of embryonic development in zebrafish

    Richard J White et al.
    Global gene expression analysis defines the transcriptional events during the development of zebrafish from fertilised egg to fully formed organism.
    1. Developmental Biology
    2. Evolutionary Biology

    Germ layer-specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm

    Miguel Salinas-Saavedra et al.
    The expression of 'bilaterian-mesodermal’ genes changes the epithelial properties of the endomesoderm during the embryogenesis of the cnidarian Nematostella vectensis.
    1. Developmental Biology

    A structure-based extracellular matrix expansion mechanism of fibrous tissue growth

    Nicholas S Kalson et al.
    Tendon fibroblast cells lay down a collagen matrix template during embryogenesis, and the expansion of this matrix drives post-natal tissue growth.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Uncoupling evolutionary changes in DNA sequence, transcription factor occupancy and enhancer activity

    Pierre Khoueiry et al.
    Interspecies comparison of transcription factor occupancy during embryogenesis reveals potential co-operative relationships between factors and uncovers the inherent plasticity of developmental enhancers to overcome divergence in transcription factor occupancy.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development

    Wenwen Zhou et al.
    The conserved mechanism of Notch down-regulation by endo-lysosomal trafficking plays important roles in the proliferation and differentiation of stem and progenitor cells during embryogenesis or organogenesis in vertebrates.