Clément Mazeaud, Stefan Pfister ... Laurent Chatel-Chaix
Through interactions with viral RNA and NS5, Zika virus changes the composition of the IGF2BP2-containing ribonucleoprotein complex for the benefit of the viral RNA amplification step of its life cycle.
A new way to treat Zika virus infections could be achieved following the definition of an ion channel function for the M protein within virus particles.
A majority of transcribed transposons during aging are derived from transcriptional defects, most notably intron retention and transcriptional readthrough.
Genetic analyses and mathematical modeling reveal that disrupting genes essential for sex determination and fertility in Aedes aegypti leads to the production of sterile males, effectively suppressing mosquito populations.
Kyra Hermanns, Marco Marklewitz ... Sandra Junglen
Analysis of naturally infected mosquitoes shows that ecosystem disturbance can lead to a turnover in host community composition and that more individuals of a single species are a key driver of virus emergence.
William D Jackson, Chiara Giacomassi ... Marina Botto
A novel pathway of emergency myelopoiesis is induced by repetitive virus stimulation at peripheral barrier sites which bypasses the requirement of conventional pathways and expands myeloid infiltration in tissues.