1,379 results found
    1. Evolutionary Biology

    Can Hamilton’s rule be violated?

    Matthijs van Veelen
    Hamilton's rule can be violated when costs and benefits of cooperation are defined using the counterfactual method, and when they depend on the cooperation of others.
    1. Neuroscience

    Empirical examination of the replicability of associations between brain structure and psychological variables

    Shahrzad Kharabian Masouleh et al.
    Empirical evaluations demonstrate the low probability of finding and replicating significant associations between psychological tests and brain structure in healthy adults, highlighting the importance out-of-sample replication of exploratory findings.
  1. Point of View: Four erroneous beliefs thwarting more trustworthy research

    Mark Yarborough et al.
    Strategies to improve public trust in biomedical research are being hindered by a scientific mindset that stifles interest in reform.
  2. Philosophy of Biology: Philosophical bias is the one bias that science cannot avoid

    Fredrik Andersen et al.
    Scientists should be aware of the non-empirical assumptions that influence all kinds of research.
    1. Computational and Systems Biology

    Meta-Research: Centralized scientific communities are less likely to generate replicable results

    Valentin Danchev et al.
    Analysis of data on drug-gene interactions suggests that decentralized collaboration will increase the robustness of scientific findings in biomedical research.
    1. Neuroscience

    Vision: Framing orientation selectivity

    Floris P de Lange, Matthias Ekman
    The ongoing debate on the neural basis of orientation selectivity in the primary visual cortex continues.
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  3. Meta-Research: How significant are the public dimensions of faculty work in review, promotion and tenure documents?

    Juan P Alperin et al.
    An analysis of review, promotion and tenure documents from 129 US and Canadian universities suggests institutions could better fulfill their public missions by changing how they incentivize the public dimensions of faculty work.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Point of View: Is cell size a spandrel?

    Ariel Amir
    Analysis of experiments on bacteria suggests that the dependence of cell size on growth rate is not an adaptation but a causal consequence of a regulatory mechanism that controls DNA replication.
    1. Biochemistry and Chemical Biology

    Ammonium Transporters: A molecular dual carriageway

    William J Allen, Ian Collinson
    In order to enter a cell, an ammonium ion must first dissociate to form an ammonia molecule and a hydrogen ion (a proton), which then pass through the cell membrane separately and recombine inside.
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    1. Medicine

    Adverse Drug Reactions: The benefits of data mining

    Audrey Bone, Keith Houck
    Careful analysis of a database populated by physicians and patients sheds new light on the side effects of drugs.
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