6,060 results found
    1. Neuroscience

    Stimulus background influences phase invariant coding by correlated neural activity

    Michael G Metzen, Maurice J Chacron
    Building on previous work (Metzen et al., 2016), a combination of neurophysiological and behavioral approaches reveals that changes in the background strongly impacts invariant coding and perception of behaviourally relevant signals.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity

    Tamara M Sirey et al.
    Mitochondrial energy metabolism is post-transcriptionally regulated through an interplay between long and short non-coding RNAs.
    1. Neuroscience

    Multiplexed coding by cerebellar Purkinje neurons

    Sungho Hong et al.
    Cerebellar Purkinje neurons use a multiplexed simple spike code combining synchrony/spike time and firing rate, with each component encoding distinct information about movements such as motion onset timing and kinematics.
    1. Cancer Biology
    2. Computational and Systems Biology

    Non-coding cancer driver candidates identified with a sample- and position-specific model of the somatic mutation rate

    Malene Juul et al.
    A new statistical approach identifies non-coding regulatory regions of genes as driver candidates with recurrent mutations across cancer samples that associate with gene expression, patient survival or mutational phenotype.
    1. Neuroscience

    Feedback optimizes neural coding and perception of natural stimuli

    Chengjie G Huang et al.
    Neurophysiological and behavioral approaches reveal how coordinated input from descending pathways shapes the tuning properties of electrosensory neurons in order to optimize coding of natural stimuli through temporal whitening.
    1. Neuroscience

    Neural variability determines coding strategies for natural self-motion in macaque monkeys

    Isabelle Mackrous et al.
    Whether central vestibular neurons implement faithful stimulus encoding for the vestibulo-occular reflex or optimized coding via temporal whitening for other vestibular functions is determined by neural variability.
    1. Neuroscience

    Neuronal variability and tuning are balanced to optimize naturalistic self-motion coding in primate vestibular pathways

    Diana E Mitchell et al.
    A match between neuronal variability and tuning enables optimized coding of natural self-motion in early vestibular pathways.
    1. Neuroscience

    Population rate-coding predicts correctly that human sound localization depends on sound intensity

    Antje Ihlefeld et al.
    Softer sound appears closer to midline than louder sound, conflicting with a labelled-line representation of auditory space and supporting the idea that humans use rate coding when calculating sound directionality.
    1. Neuroscience

    Large-scale network integration in the human brain tracks temporal fluctuations in memory encoding performance

    Ruedeerat Keerativittayayut et al.
    Graph analysis revealed that spontaneous fluctuations of episodic-memory encoding performance associate with time-varying brain connectivity networks.
    1. Evolutionary Biology

    Long non-coding RNAs as a source of new peptides

    Jorge Ruiz-Orera et al.
    Ribosome profiling data from several eukaryotic species provides strong evidence that many long non-coding RNA molecules encode novel short proteins.

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