322 results found
    1. Evolutionary Biology

    Quantifying the relationship between genetic diversity and population size suggests natural selection cannot explain Lewontin’s Paradox

    Vince Buffalo
    Quantifying the relationship between census sizes and genetic diversity estimates provides insights into whether natural selection can explain the narrow range of diversity between species.
    1. Microbiology and Infectious Disease

    Typhoid toxin sorting and exocytic transport from Salmonella Typhi-infected cells

    Shu-Jung Chang, Yu-Ting Hsu ... Jorge E Galan
    A multidisciplinary approach provides a description of the exocytic pathway that exports Salmonella Typhi's typhoid toxin from infected cells.
    1. Neuroscience

    Neuroanatomy of a hydrothermal vent shrimp provides insights into the evolution of crustacean integrative brain centers

    Julia Machon, Jakob Krieger ... Steffen Harzsch
    A neuroanatomical analysis of Rimicaris exoculata provides insights into these animal’s brain architecture to illustrate possible adaptations to the hydrothermal vent habitat with its extreme physicochemical conditions.
    1. Evolutionary Biology
    2. Neuroscience

    Divergent sensory investment mirrors potential speciation via niche partitioning across Drosophila

    Ian W Keesey, Veit Grabe ... Bill S Hansson
    Phototaxis and courtship behavioral preferences reflect strong correlation with differences in olfactory and visual nervous system investment across five monophyletic Drosophila species, and could help explain their speciation events.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Major genetic discontinuity and novel toxigenic species in Clostridioides difficile taxonomy

    Daniel R Knight, Korakrit Imwattana ... Thomas V Riley
    The Clostridioides difficile taxonomy is characterised by major taxonomic incoherence and clear species boundaries.
    1. Ecology
    2. Epidemiology and Global Health

    Antagonism between parasites within snail hosts impacts the transmission of human schistosomiasis

    Martina R Laidemitt, Larissa C Anderson ... Eric S Loker
    Interactions among parasites in snails create cascading effects on their transmission and highlight that biodiversity has complex, context-dependent and important effects on human schistosomiasis transmission dynamics.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Ancient DNA reveals the lost domestication history of South American camelids in Northern Chile and across the Andes

    Paloma Diaz-Maroto, Alba Rey-Iglesia ... Anders J Hansen
    aDNA revealed a model of domestication where an ancient guanaco population no longer exists, the loss of the ancient vicuña genetic variation in the modern populations, and frequently interbreeding practices.
    1. Ecology
    2. Immunology and Inflammation

    Hematodinium sp. infection does not drive collateral disease contraction in a crustacean host

    Charlotte E Davies, Jessica E Thomas ... Christopher J Coates
    Neither the presence nor the intensity of Hematodinium sp. parasitisation drives co-infection occurrence, severity, or diversity in the ecologically ubiquitous shore crab, Carcinus maenas.
    1. Immunology and Inflammation

    Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection

    Ana-Carolina Oliveira, João Francisco Gomes-Neto ... Maria Bellio
    Development of a robust Th1 response to infection against an intracellular parasite requires T-cell intrinsic MyD88 signaling, mostly through the upstream IL-18 receptor, for the induction of genes involved in proliferation, cytokine production and migration.
    1. Microbiology and Infectious Disease

    PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in a drug-tolerant hepatocyte environment

    Binayak Sarkar, Jyotsna Singh ... Rajesh S Gokhale
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing

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