250 results found
    1. Genetics and Genomics
    2. Neuroscience

    Antagonist actions of CMK-1/CaMKI and TAX-6/Calcineurin along the C. elegans thermal avoidance circuit orchestrate nociceptive habituation

    Martina Rudgalvyte, Zehan Hu ... Dominique A Glauser
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Deficiency of orexin receptor type 1 in dopaminergic neurons increases novelty-induced locomotion and exploration

    Xing Xiao, Gagik Yeghiazaryan ... Anne Christine Hausen
    Ox1R signaling in dopaminergic neurons regulates context-induced locomotor activity and exploration in mice.
    Version of Record
    Short Report
    • Valuable
    • Solid
    1. Neuroscience

    TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyes

    Christopher N Rudzitis, Monika Lakk ... David Križaj
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Neuroscience

    Prolactin-mediates a lactation-induced suppression of arcuate kisspeptin neuronal activity necessary for lactational infertility in mice

    Eleni Hackwell, Sharon R Ladyman ... David R Grattan
    Lactational infertility in mice is dependent on prolactin action in kisspeptin neurons.
    1. Neuroscience

    Input-specific gating of NMDA amplification via HCN channels in mouse L2/3 pyramidal neurons

    Viktor János Oláh, Jing Wu ... Matthew JM Rowan
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    Hypersensitive intercellular responses of endometrial stromal cells drive invasion in endometriosis

    Chun-Wei Chen, Jeffery B Chavez ... Bruce J Nicholson
    A unique functional comparison of the major endometrial cell types from 44 control and endometriosis patients demonstrates not only a uterine origin of the disease, but also that endometrial to mesothelial cell gap junctions are required for invasive lesion formation.
    1. Neuroscience

    Sigh generation in preBötzinger Complex

    Yan Cui, Evgeny Bondarenko ... Jack L Feldman
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Computational and Systems Biology

    MGPfactXMBD: A Model-Based Factorization Method for scRNA Data Unveils Bifurcating Transcriptional Modules Underlying Cell Fate Determination

    Jun Ren, Ying Zhou ... Qiyuan Li
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology
    2. Medicine

    Disruption of the Novel Nested Gene Aff3ir Mediates Disturbed Flow-Induced Atherosclerosis in Mice

    Shuo He, Lei Huang ... Jinlong He
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Inadequate
    1. Neuroscience

    Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive effects

    Brian C Ruyle, Sarah Masud ... Jose A Moron
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
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