Single-unit activity in the ventrolateral periaqueductal gray, a brain region implicated in organizing fear output, is found to reflect threat probability, a more versatile threat signal.

The bidirectional orbitofrontal cortex-basolateral amygdala circuit helps us to learn the details of predicted rewarding events and then to use that information to make good reward pursuit decisions.

The VTA-mOT DAergic pathway mediates a variety of naturalistic reward processes and different types of preferences including odor-preference.

TRPV channels share general mechanisms of activation while exhibiting subtype-specific features along the activation pathway that can determine their apparent sensitivity to stimuli.

A conceptual framework and physical model shows how actin-spectrin networks and microtubule bundles can protect axons from mechanical stress.

Cryo-electron microscopic structures of 5-HT₃A receptor in complex with first and second generations of clinically used setron reveal the molecular basis for their binding modes and mechanisms of inhibitory action.

Molecular, cellular and behavioral genetic approaches in Platynereis dumerilii indicate that r-Opsins can act as ancient, light-dependent modulators of mechanosensation, and suggest that light-independent mechanosensory roles of r-Opsins evolved secondarily.