Glucocorticoids are assumed to reflect 'stress,' but they increase proportionally to the increase in metabolic rate induced by stressors, leading us to propose that glucocorticoids reflect metabolic rate, not stress.
Shamayeeta Ray, Samuel P Berry ... Rachelle Gaudet
Structures of a transition metal transporter spanning the entire Mn2+ transport cycle reveal distinct coordination geometries and dynamic polar networks that enable Mn2+ import, and a Cd2+-bound structure helps explain how Cd2+ behaves differently as a substrate.
The tail domain of Myosin III binds to and cross-links actin bundling protein Espin1 and thus modulates higher order actin bundle structures in cellular processes such as stereocilia and microvilli.
During the evolution of amniotes, the transformation of branchial arches coincided with the drastic remodeling of the ancestral extrinsic cardiac arteries, giving rise to novel ventricular coronary arteries that are unique to amniotes.
A reflection on eLife's achievements in 2017, notably in convening and supporting communities, modernising technology for research communication and partnering with early-career researchers.