1,217 results found
    1. Neuroscience

    Enhancement of fear memory by retrieval through reconsolidation

    Hotaka Fukushima et al.
    Retrieval enhances fear memory through reconsolidation by activating calcineurin-induced protein degradation and CREB-mediated gene expression in amygdala, hippocampus, and mPFC.
    1. Neuroscience

    Chronic pain induces generalized enhancement of aversion

    Qiaosheng Zhang et al.
    Chronic pain distorts intensity coding in the anterior cingulate cortex to give rise to generalized anatomically nonspecific enhancement in pain aversion.
    1. Neuroscience

    A role for CIM6P/IGF2 receptor in memory consolidation and enhancement

    Xiao-Wen Yu et al.
    Cation-independent-mannose-6-phosphate-receptor, or insulin-like-growth-factor-2-receptor (CIM6P/IGF2R) expressed in the hippocampus controls the protein metabolism regulated by learning and required for memory consolidation, and is also a key mechanism for memory enhancement.
    1. Neuroscience

    A cross-modality enhancement of defensive flight via parvalbumin neurons in zona incerta

    Xiyue Wang et al.
    Parvalbumin positive GABAergic neurons in the ventral zona incerta receive input from somatosensory cortex and enhance sound-induced flight behavior, which underlies a cross-modality facilitation of defensive behavior by somatosensory input.
    1. Neuroscience

    Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter release

    Özgür Genç et al.
    Protein kinase C brings about post-tetanic potentiation - a temporary increase in synaptic strength due to increased transmitter release - via phosphorylation of a target protein, Munc18-1.
    1. Chromosomes and Gene Expression

    Enhancement of homology-directed repair with chromatin donor templates in cells

    Grisel Cruz-Becerra, James T Kadonaga
    Precise genome editing by homology-directed repair occurs more efficiently with a chromatin donor template than with a naked DNA donor template.
    1. Neuroscience

    Anxiety dissociates the adaptive functions of sensory and motor response enhancements to social threats

    Marwa El Zein et al.
    Social threats trigger enhanced neural representations within 200 milliseconds in sensory and motor systems of the human brain as a function of anxiety, highlighting its adaptive function in reacting rapidly to dangers in the environment.
    1. Neuroscience

    Enhancement of encoding and retrieval functions through theta phase-specific manipulation of hippocampus

    Joshua H Siegle, Matthew A Wilson
    The ability of mice to encode new memories or retrieve existing ones can be selectively manipulated by using optogenetics to inhibit hippocampal activity at specific phases of the theta cycle.
    1. Structural Biology and Molecular Biophysics

    Encounter complexes and dimensionality reduction in protein–protein association

    Dima Kozakov et al.
    Analysis of protein–protein encounter complexes shows that proteins associate along preferred pathways, similar to the sliding of a protein along DNA.
    1. Neuroscience

    Push-pull competition between bottom-up and top-down auditory attention to natural soundscapes

    Nicholas Huang, Mounya Elhilali
    Everyday soundscapes dynamically engage attention towards target sounds or salient ambient events, with both attentional forms engaging the same fronto-parietal network but in a push-pull competition for limited neural resources.

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