A new system for tagging activated neuronal population offers multiple advantages over existing systems based on immediate early genes, including greater sensitivity and specificity, and suitability for easy application in species other than mice.

Neuron populations in the lateral entorhinal cortex discriminate between memory-based contexts through both continuous "tonic" activity patterns as well as by their stimulus-evoked "phasic" responses.

Auditory cortical columns contain small subsets of neurons with highly synchronous activity (cNEs) that create robust sequences of coordinated activity suitable for enhanced information processing and signal transmission beyond the capability of individual neurons.

An ensemble of cryo-EM structures reveals how eukaryotic elongation factor 2 positions the first codon of a viral mRNA for translation.

Neuron ensembles in the medial prefrontal cortex gradually develop codes for relevant, latent variables common across multiple experiences while – apparently independently – losing information about irrelevant, contextual variables unique to each experience.

To control centriole duplication, centriolar satellite proteins assemble a microcephaly-associated protein complex at the centrosome and activate cyclin-dependent kinase 2.

In vivo calcium imaging reveals how odor identity is encoded in the activity of large, distributed ensembles of olfactory cortex neurons in mice.

Lys63-linked diubiquitin exists as an ensemble of conformational states, each responsible for binding to a target protein through conformational selection.

Optogenetic reconstitution reveals core functional modules and architecture of the cortical force-generating machinery in human cells.

A brain–computer interface for real-time identification of transient neural activity patterns enables causal inference of the role of these patterns in cognition through closed-loop manipulation.