Susan Martin, Jessica Tyrrell ... Hanieh Yaghootkar
Using genetics, it is possible to uncouple higher adiposity from its adverse metabolic effects and show that some obesity-associated conditions may benefit from treating the metabolic effects alone, whilst others may benefit more from weight loss.
The animal phylogeny of glutamate receptors indicates that vertebrate types do not account for all receptor classes originated during evolution, neither are they the pinnacle of a linear evolutive process.
In causal inference, the premotor cortex dynamically integrates prior information and current sensory inputs to infer hidden structures, and selectively updates sensory representations in the parietal cortex to support behavior.
The prediction of specific words is associated with distinct spatial and temporal patterns of neural activity within the left inferior and medial temporal regions before the predicted word is presented.
Abraham Escobedo, Salli-Ann Holloway ... Aaron J Norris
Activation of a population of glutamatergic neurons in supramammillary nucleus enhances active coping behaviors in response to threats, offering new insights for therapeutic strategies against anxiety and mood disorders.
Richard CV Tyser, Antonio MA Miranda ... Paul R Riley
High-resolution live imaging reveals how and when the mouse heart first starts to beat during development and how the onset of beating impacts on heart muscle cell maturation and heart formation.
Feedback-driven gain modulation provides a mechanism to generate and maintain invariant sensory representations in the presence of contextual changes by dynamically adapting feedforward sensory processing.
A naturally acquired human monoclonal antibody recognizes proteins expressed at different stages of the Plasmodium falciparum life cycle through affinity-matured homotypic interactions with glutamate-rich repeats.
Soo Ji Baek, Jin Sung Park ... Keiko Tanaka-Yamamoto
Long-term chemogenetic manipulation of specific cerebellar pathway involving ventral tegmental area revealed a critical role of the pathway as a proactive mediator of the stress-dependent development of depression-like behaviors.
