3,744 results found
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Mapping global environmental suitability for Zika virus

    Jane P Messina, Moritz UG Kraemer ... Simon I Hay
    A global map of environmental suitability for Zika virus and the estimated population living at potential risk can help refine public health guidelines, travel advisories and intervention strategies at a crucial time in the global emergence of this arbovirus.
    1. Ecology

    Temperature sensitivity of the interspecific interaction strength of coastal marine fish communities

    Masayuki Ushio, Testuya Sado ... Masaki Miya
    Fish environmental DNA remaining in a cup of seawater provides information about interaction strengths among marine fish species in nature, highlighting the potential impact of global climate change on community dynamics and stability.
    1. Ecology
    2. Evolutionary Biology

    The evolution of distributed sensing and collective computation in animal populations

    Andrew M Hein, Sara Brin Rosenthal ... Iain D Couzin
    A computational model shows that natural selection can cause populations to evolve a distinctive population-level phenotype: the ability to transition between collective states in response to the environment.
    1. Neuroscience

    Auditory mismatch responses are differentially sensitive to changes in muscarinic acetylcholine versus dopamine receptor function

    Lilian Aline Weber, Sara Tomiello ... Klaas Enno Stephan
    Biperiden, but not amisulpride, delays auditory mismatch responses during environmental stability, suggesting a differential sensitivity of auditory statistical learning to muscarinic versus dopaminergic receptor status which could prove useful for developing tests that predict an individual's response to antipsychotic treatment.
    1. Neuroscience

    On the normative advantages of dopamine and striatal opponency for learning and choice

    Alana Jaskir, Michael J Frank
    A computational model of the opponent neural architecture the basal ganglia, in tandem with adaptive dopamine modulation, exhibits robust advantages over traditional learning algorithms and ties together seemingly aberrant behavioral patterns resulting from dopamine and environmental manipulations across species.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Mechanistic theory predicts the effects of temperature and humidity on inactivation of SARS-CoV-2 and other enveloped viruses

    Dylan H Morris, Kwe Claude Yinda ... James O Lloyd-Smith
    Viruses, including SARS-CoV-2, retain infectivity longer at low temperatures and extreme relative humidities because these conditions slow down the chemical reactions that inactivate those viruses.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Evolution of multicellularity by collective integration of spatial information

    Enrico Sandro Colizzi, Renske MA Vroomans, Roeland MH Merks
    Selection for undifferentiated multicellularity emerges in an evolutionary cell-based model because a collective of cells performs chemotaxis better than single cells in a noisy environment.
    1. Neuroscience

    Network instability dynamics drive a transient bursting period in the developing hippocampus in vivo

    Jürgen Graf, Vahid Rahmati ... Knut Kirmse
    Two-photon Ca2+ imaging and computational modeling reveal major developmental trajectories of spontaneous activity in developing CA1 and identify important roles of network bi-stability and synaptic input characteristics for hippocampal burstiness before eye opening.
    1. Medicine

    Loss of adaptive capacity in asthmatic patients revealed by biomarker fluctuation dynamics after rhinovirus challenge

    Anirban Sinha, René Lutter ... Edgar Delgado Eckert
    Fluctuation of biomarkers is a novel way of studying system stability during stable and unstable states of health and disease, revealing the systems' ability to cope with external perturbations.
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    Functional trade-offs and environmental variation shaped ancient trajectories in the evolution of dim-light vision

    Gianni M Castiglione, Belinda SW Chang
    The evolution of the light-sensitive visual pigment rhodopsin involved functional tradeoffs that may have sacrificed rod photosensitivity for active-state protein stability to mitigate phototoxicity in tetrapods, but not in fishes.

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