Soon after fertilisation, a critical portion of the embryonic genome is switched on through the actions of maternally inherited Stella, in part through controlling the activation of transposable elements.

In Aves, the first wave of transcription is derived exclusively from the maternal genome.

The vertebrate neural plate border is comprised of precursors that coexpress multiple lineage markers and small changes in their levels can bias border cell fate.

DNA methylation deposition is dependent on the presence of H3K4me3 and H3K36me3 histone marks.

A novel lncRNA (Ephemeron) is connected to known post-transcriptional and epigenetic regulators as part of an integrated machinery, which controls the timely exit from the naïve state of mouse embryonic stem cells.

A tumor-specific regulatory region has been identified upstream of the Myc oncogene.

PCGF6 links sequence specific target recognition by the MAX/MGA transcription factor complex to PRC1 (polycomb repressive complex 1) -dependent transcriptional silencing of germ cell-specific genes in mouse pluripotent stem cells.

Mice deficient in the TRPM6 channel suffer from impaired prenatal development, shortened lifespan, growth deficit and disturbed energy balance due to a defect in epithelial Mg²⁺ uptake, thus highlighting a pivotal role of TRPM6 in organismal Mg²⁺ homeostasis.

Polycomb enables lineage priming in mouse embryonic stem cells by establishing a barrier to commitment.

The Hippo pathway downstream effector YAP regulates S-phase progression to protect neural stem cells of the retina from experiencing genomic instability.