Estimating fine-scale spatiotemporal patterns of Plasmodium falciparum transmission showed an association between entomological inoculation rate and parasite prevalence that emphasizes the value of both measures in malaria surveillance.
Preimplantation screening of embryos using polygenic risk scores may substantially reduce risk for a given complex disease, but this effect depends on several quantifiable factors and raises significant ethical issues.
COVID-19 severity, rather than sex or age, predicts SARS-CoV-2 kinetics, and SARS-CoV-2 viral load from lower respiratory tract specimens may predict severe disease days before clinical deterioration for COVID-19 patients.
Carriage of MDR S. Typhi H58 sublineages that also cause acute disease provides understanding of the transmission dynamics of typhoid fever and maintenance of local pathogen populations in Kenya children.
Bayesian estimation of the proportion of the population that would show an effect in an experiment provides a broadly applicable alternative to standard null hypothesis tests on the population mean with several advantages.