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    1. Genetics and Genomics
    2. Plant Biology

    Stress induced gene expression drives transient DNA methylation changes at adjacent repetitive elements

    David Secco, Chuang Wang ... Ryan Lister
    Phosphate starvation in rice induces widespread, but transient, modulation of DNA methylation near stress responsive genes that is independent from the RNA-directed DNA methylation pathway.
    1. Genetics and Genomics
    2. Neuroscience

    Antipsychotic-induced epigenomic reorganization in frontal cortex of individuals with schizophrenia

    Bohan Zhu, Richard I Ainsworth ... Javier González-Maeso
    Age and antipsychotic treatment effects on chromatin organization in the frontal cortex of schizophrenia subjects.
    1. Genetics and Genomics
    2. Neuroscience

    Epigenomic landscapes of retinal rods and cones

    Alisa Mo, Chongyuan Luo ... Jeremy Nathans
    Genome-wide analysis of DNA methylation and accessible chromatin shows that retinal rods and cones have distinct epigenomic features that reflect differences in their development and function.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Effects of smoking on genome-wide DNA methylation profiles: A study of discordant and concordant monozygotic twin pairs

    Jenny van Dongen, Gonneke Willemsen ... Michael C Neale
    Analysis of data from monozygotic twins reveals that DNA methylation level in human blood cells is reactive to cigarette smoking.
    1. Chromosomes and Gene Expression

    DNA methylation-environment interactions in the human genome

    Rachel A Johnston, Katherine A Aracena ... Jenny Tung
    A massively parallel reporter assay, mSTARR-seq, reveals widespread DNA methylation-environment interactions across the genome, prioritizing CpG sites identified in epigenome-wide association studies that may be most relevant to biological embedding.
    1. Developmental Biology

    Mechanistic target of rapamycin (mTOR) pathway in Sertoli cells regulates age-dependent changes in sperm DNA methylation

    Saira Amir, Olatunbosun Arowolo ... Alexander Suvorov
    For the first time, a molecular mechanism is identified, for experimental acceleration and deceleration (rejuvenation) of sperm epigenetic aging.
    1. Plant Biology

    DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis

    Amr Nassrallah, Martin Rougée ... Fredy Barneche
    Light signaling components interact with a histone H2B deubiquitination module, adjusting chromatin states at global level during Arabidopsis seedling development.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    A unique chromatin profile defines adaptive genomic regions in a fungal plant pathogen

    David E Cook, H Martin Kramer ... Bart P H J Thomma
    Assessment of DNA methylation, histone modifications, and DNA accessibility revealed that physical DNA characteristics are associated with adaptive genome evolution in the broad host range plant pathogenic fungus Verticillium dahliae.
    1. Immunology and Inflammation

    Autoimmunity: The epigenetic trajectory of type 1 regulatory T cells

    David P Turicek, Xiaoxiao Wan
    The epigenome of T follicular helper cells prepares them for conversion into type 1 regulatory T cells.
    Version of Record
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    1. Genetics and Genomics
    2. Stem Cells and Regenerative Medicine

    Multi-omic rejuvenation of human cells by maturation phase transient reprogramming

    Diljeet Gill, Aled Parry ... Wolf Reik
    Transiently reprogramming human fibroblasts up to the maturation phase rejuvenates cells according to several aging markers whilst enabling them to return to their original identity.