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    1. Chromosomes and Gene Expression

    The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer

    Eric Wang et al.
    TRIM33 performs an essential function in B cell acute lymphoblastic leukemia through an association with a single cis element.
    1. Human Biology and Medicine

    KRAS-dependent sorting of miRNA to exosomes

    Diana J Cha et al.
    In isogenically matched colorectal cancer (CRC) cell lines, mutant KRAS alters the composition of secreted miRNAs in extracellular vesicles that can then transfer repressive activity to wild type cells.
    1. Cancer Biology

    KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer

    Elsa B Krall et al.
    Loss of KEAP1 modulates sensitivity to targeted therapies in lung cancer.
    1. Developmental Biology
    2. Structural Biology and Molecular Biophysics

    A crystal structure of a collaborative RNA regulatory complex reveals mechanisms to refine target specificity

    Chen Qiu et al.
    A Caenorhabitis elegans RNA-binding protein, FBF-2, modulates RNA sequence motif recognition through conformational change and partner protein interaction.
    1. Developmental Biology
    2. Structural Biology and Molecular Biophysics

    Engineering a conserved RNA regulatory protein repurposes its biological function in vivo

    Vandita D Bhat et al.
    Motif length plays a critical role in the specification of biological function within a conserved family of RNA-binding proteins.
    1. Cancer Biology

    MELK expression correlates with tumor mitotic activity but is not required for cancer growth

    Christopher J Giuliano et al.
    Cancer cells can grow in vitro and in vivo in the absence of maternal embryonic leucine zipper kinase (MELK).
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Chromosome territory formation attenuates the translocation potential of cells

    Leah F Rosin et al.
    The translocation potential of cells can be modulated by Condensin II activity during interphase.
    1. Stem Cells and Regenerative Medicine

    Transgenerational dynamics of rDNA copy number in Drosophila male germline stem cells

    Kevin L Lu et al.
    rDNA copy number is shown to dynamically change during aging and through generations, and is actively maintained in male germline of Drosophila.