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Human Intelligence: What single neurons can tell us
Elaine N Miller, Chet C Sherwood
IQ scores are correlated with the morphology and activity of certain neurons in the human temporal cortex.
Living Science: The humanity of science
Indira M Raman
Science can provide cures and improve health, and it can also make us more humane.
Structural Biology and Molecular Biophysics
Ion Channels: Exploiting natural regulation
Using a short peptide to regulate the activity of HCN ion channels illustrates how physiological modulators could inspire new drugs. .
The Natural History of Model Organisms:
mice as a model for studying natural variation
Nicole L Bedford, Hopi E Hoekstra
The deer mouse (
) has emerged as a model system for studying many aspects of biology, supported by extensive historical knowledge of its fascinating and varied natural history.
Perception: Tell me something I don’t know
Ragulator and GATOR1 complexes promote fission yeast growth by attenuating TOR complex 1 through Rag GTPases
Kim Hou Chia et al.
The Rag-family GTPases, known activators of TOR complex 1 (TORC1), also function as attenuator that prevents deregulated hyperactivation of TORC1 signaling.
Biophysics of object segmentation in a collision-detecting neuron
Richard Burkett Dewell, Fabrizio Gabbiani
Active dendritic processing enables an individual neuron to discriminate the spatial pattern of synaptic inputs, increasing neural and behavioral selectivity for escaping an impending threat.
High lumenal chloride in the lysosome is critical for lysosome function
Kasturi Chakraborty et al.
Lysosomes are highly enriched in chloride, which is essential for their degradative function.
The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors
Heather S Comstra et al.
The ATP7A interactome is the first comprehensive view of putative Menkes disease neurodegeneration mechanisms.
Inhibitory peptidergic modulation of
serotonin neurons is gated by T-type calcium channels
Kara E Zang et al.
Genetic analysis of how neuropeptides control
reproductive behavior shows how T-type calcium channels engage and disengage target neurons from these critical regulators of neural circuits and behavior.
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