155 results found
    1. Neuroscience

    Development of schemas revealed by prior experience and NMDA receptor knock-out

    George Dragoi, Susumu Tonegawa
    Novel spatial representations by hippocampal cellular assemblies develop on the framework of preconfigured hippocampal networks whose homeostatic synaptic reorganization is accelerated by prior experience and CA3 NMDAR-dependent plasticity.
    1. Neuroscience

    Reconceiving the hippocampal map as a topological template

    Yuri Dabaghian, Vicky L Brandt, Loren M Frank
    Empirical evidence suggests that the hippocampus constructs maps of spatial environments based on the relative locations of places (i.e., topology), rather than absolute distances and coordinates (i.e., geometry).
    1. Neuroscience

    Neural mechanisms of economic commitment in the human medial prefrontal cortex

    Konstantinos Tsetsos, Valentin Wyart ... Christopher Summerfield
    A striking dissociation exists in the medial prefrontal cortex, with different brain regions responding to value when commitments are deferred to the future and when prospects are judged to be undesirable.
    1. Neuroscience

    Delay-dependent contributions of medial temporal lobe regions to episodic memory retrieval

    Maureen Ritchey, Maria E Montchal ... Charan Ranganath
    The anterior and posterior parts of the hippocampus have distinct roles in the retrieval of contextual information in memories of recent experiences.
    1. Ecology
    2. Epidemiology and Global Health

    Effectiveness of traveller screening for emerging pathogens is shaped by epidemiology and natural history of infection

    Katelyn M Gostic, Adam J Kucharski, James O Lloyd-Smith
    Pathogen natural history, epidemiological knowledge, human behavior and epidemic progression determine whether symptom screening and questionnaires are effective barriers to geographic spread of infection by travelers.
    1. Neuroscience

    Recruitment of the default mode network during a demanding act of executive control

    Ben M Crittenden, Daniel J Mitchell, John Duncan
    The default mode network in the brain is activated during the performance of executive-type tasks when a substantial change in cognitive contents is required.
    1. Neuroscience

    Hippocampome.org: a knowledge base of neuron types in the rodent hippocampus

    Diek W Wheeler, Charise M White ... Giorgio A Ascoli
    Hippocampome.org is an online resource that provides free human- and machine-readable access to the comprehensive property-based classification of hippocampal neurons from 14,000 pieces of published experimental evidence.
    1. Neuroscience

    A molecular mechanism underlying gustatory memory trace for an association in the insular cortex

    Chinnakkaruppan Adaikkan, Kobi Rosenblum
    The role of CaMKII-GluA1 in the cortex in maintaining a given taste memory trace for an aversive association has been elucidated.
    1. Neuroscience

    A nap to recap or how reward regulates hippocampal-prefrontal memory networks during daytime sleep in humans

    Kinga Igloi, Giulia Gaggioni ... Sophie Schwartz
    Sleep plays a critical role in the selectivity of memory by promoting the retention of important memories at the expense of less relevant ones.
    1. Neuroscience

    Schematic memory components converge within angular gyrus during retrieval

    Isabella C Wagner, Mariët van Buuren ... Guillén Fernández
    Upon retrieval, the angular gyrus recombines distinct, consolidated schema components into one memory representation.

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