Prefrontal causal roles in bistable perception are dynamically changing and determined by the brain state to which the whole-brain activity pattern belongs.
Kaspar E Vogt, Ashwinikumar Kulkarni ... Robert W Greene
Sleep's role to down-scale glutamate, excitatory, frontal cortical synapses is extended to include an up-scaling of metaplastic LTP potential, in recovery from prolonged waking induced saturation of this LTP potential.
Jamie L Courtland, Tyler WA Bradshaw ... Scott H Soderling
Cellular etiology of a human WASH complex mutation in mice reveals its specific roles in neuronal organelle trafficking and a surprising role in motor impairments.
A two-part neural network models reward-based training and provides a unified framework in which to study diverse computations that can be compared to electrophysiological recordings from behaving animals.
Independent dating techniques have established that the H. naledi fossils are between 236 and 335 thousand years old, indicating that small-brained hominins with relatively primitive body shapes co-existed with our early ancestors in Africa.
Automated computational unfolding of the hippocampus allows analyses at its mesoscale and facilitates novel discoveries in the study of cognition and disease.
Valerie A Larson, Yevgeniya Mironova ... Dwight E Bergles
Oligodendrocytes in white matter use Kir4.1 inwardly rectifying potassium channels to prevent extracellular potassium accumulation, enabling neurons to sustain repetitive firing and limiting the initiation of seizures.
Ryan T Dosumu-Johnson, Andrea E Cocoran ... Susan M Dymecki
Pet1 neurons actively maintain cardiorespiratory tone and dynamic range in mouse neonates and critically support the recovery response to apneas, informing brain findings in the sudden infant death syndrome.