Neurons in the mouse hippocampus, known as place cells, surprisingly show movie-fields, where they reliably encode distinct segments of a black-and-white, silent movie, even without any task demand or rewards.
Franziska R Richter, Rose A Cooper ... Jon S Simons
Combining fMRI with continuous model-based measures of retrieval enables the behavioral and neural dissociation of multiple components of episodic memory.
High-resolution fMRI data reveal an often-neglected contribution of the medial temporal lobe circuitry to item-specific representation in visual working memory, suggesting the mechanism traditionally deemed dedicated to long-term memory can be exploited to support the quality of human working memory.
Gail M Rosenbaum, Hannah L Grassie, Catherine A Hartley
Relative to children and adults, adolescents placed greater weight on negative prediction errors during learning and these age-varying learning idiosyncrasies biased subsequent memory for information associated with valenced outcomes.
Lyndsey Aponik-Gremillion, Yvonne Y Chen ... Brett L Foster
Invasive recordings from human dorsal posterior cingulate cortex show neural population responses occur for only executive tasks, while single neuron responses occur for specific executive or episodic cognitive tasks.
Empirical evidence suggests that the hippocampus constructs maps of spatial environments based on the relative locations of places (i.e., topology), rather than absolute distances and coordinates (i.e., geometry).
Stephanie L Leal, Susan M Landau ... William J Jagust
Cognitively normal older adults show a positive relationship between neural activity during memory encoding and brain β-amyloid deposition rate over the subsequent 3-4 years, supporting preclinical data that associates neural activity with β-amyloid deposition.
Human intracranial electroencephalography recordings across 177 participants and four diverse episodic memory experiments demonstrate how the anterior insula node of the salience network orchestrates dynamics of large-scale brain networks.
Among three new models for KCNMA1 channelopathy, the most severe gain-of-function variant (Kcnma1N999S/WT) displays a particular type of immobilizing paroxysmal dyskinesia observed in patients, including amphetamine responsiveness.
