415 results found
    1. Cell Biology
    2. Developmental Biology and Stem Cells

    Cell volume changes contribute to epithelial morphogenesis in zebrafish Kupffer’s vesicle

    Agnik Dasgupta et al.
    During Kupffer's vesicle morphogenesis, cell volume anisotropy impacts cell shape changes.
    1. Developmental Biology and Stem Cells

    Organ Size: Connecting physical cues and tissue patterning

    Damian Dalle Nogare, Ajay B Chitnis
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    1. Biophysics and Structural Biology
    2. Immunology and Inflammation

    Immune Response: An ambulance for retinol

    Stephanie C Ganal, Andrew J MacPherson
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    1. Cell Biology

    Cell Biology: A new regulator of caveolae signalling

    Alan J Whitmarsh
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    1. Cell Biology
    2. Computational and Systems Biology

    Science Forum: The Human Cell Atlas

    Aviv Regev et al.
    Advances in techniques for analysing single cells and tissues have inspired an international effort to create comprehensive reference maps of all human cells - the fundamental units of life - as a basis for both understanding human health and diagnosing, monitoring and treating disease.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Science Forum: Viral factors in influenza pandemic risk assessment

    Marc Lipsitch et al.
    We identify key strengths and limitations in use of viral genotyping and phenotyping to estimate pandemic risk from influenza A viruses, focusing on 3 traits, hemagglutinin binding specificity, hemagglutinin pH of activation, and polymerase complex efficiency.
    1. Genomics and Evolutionary Biology
    2. Microbiology and Infectious Disease

    The Natural History of Model Organisms: The unexhausted potential of E. coli

    Zachary D Blount
    A better understanding of the remarkable diversity, natural history and complex ecology of E. coli in the wild could shed new light on its biology and role in disease, and further expand its many uses as a model organism.
    1. Genes and Chromosomes

    Cooperative interactions enable singular olfactory receptor expression in mouse olfactory neurons

    Kevin Monahan et al.
    Biochemical and genetic experiments show that Ebf and Lhx2 cooperate to specify olfactory receptor enhancers, which cooperate to drive olfactory receptor expression.
    1. Cancer Biology

    NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma

    Zhi-Jie Xiao et al.
    NFATc2 maintains the drug-induced TIC phenotypes through trans-activating SOX2/ALDH1A1 expression and scavenging stress from ROS.
    1. Developmental Biology and Stem Cells

    Neural stem cells induce the formation of their physical niche during organogenesis

    Ali Seleit et al.
    A physical niche for neural stem cells is generated by the induction of the immediate skin epithelium, a process triggered by the arrival of neural precursors during sensory organ formation in medaka.

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