A combination of computational approaches identifies a novel allosteric hotspot in cystic fibrosis transmembrane conductance regulator.

Bioinformatics analyses and experiments in mouse models reveal how Escherichia coli accesses the molecular hydrogen pool to boost colonization during acute colitis.

A model of efficient coding by olfactory neurons explains context-dependence observed in the effect of perturbations to the olfactory environment.

Dystonin-b-specific mutant mice exhibit late-onset myopathy and cardiomyopathy.

The striking reduction in open probability of CFTR channels harboring the R117H cystic fibrosis mutation is caused by loss of a strong hydrogen bond between positions 117 and 1124, which is formed in wild-type channels selectively in the open state.

Electric signals produced by weakly electric gymnotiform fish, long seen as communication attempts, may also serve to localize conspecifics, revealing a distinct functional role.

A worm with a nervous system of only 302 neurons satisfies the necessary and sufficient conditions for value-based decision making.

Fixed, intact animals of C. elegans can be physically expanded with high isotropy, to enable super-resolved imaging of general proteins and nucleic acids throughout the organism, on conventional microscopes.