Single-cell tracking and cell-fate simulation suggest that low levels of p53 suppress aneuploid cell formation in unstressed cells and also reveal the dual fate of cells lacking p53 in the presence of p53-proficient cells.

A novel role of the mitochondrial BK_Ca channel involves the metabolic reprogramming of breast cancer cells, facilitating their unrestricted proliferation and O₂-independence, which is also of potential clinical relevance.

Localized temperature gradients used as a novel method of active micro-theology that is non-invasive and probe-free, to investigate material responses of cell departments such as the different compartments of a nucleus displaying distinct material properties.

The Botryllus schlosseri genome yields insights into the evolution of hematopoiesis.

Therapeutic potential of CCL3 for the treatment of diabetic foot ulcers if it is applied topically after the surgical debridement.

A high-throughput mitochondrial phenotyping approach quantifies mitochondrial features among purified human immune cell subtypes and provides foundational knowledge to map inter- and intra-individual variation in mitochondrial energetics with high biological specificity.

Anatomical study reveals a new perspective on the definition of an electrical synapse where, in addition to the communicating role of gap junctions, additional cellular structures might be involved in the support and regulation of these intercellular channels.

BDNF-regulated deployment of Rab10 to the distal axon regulates retrograde propagation of neurotrophic signalling, providing a flexible mechanism to fine-tune the communication between the synapse and the cell body of neurons, as well as novel therapeutic targets for neurodegeneration.

Zebrafish have a physiological time-window of 1 hr for breaking left-right symmetry and are highly sensitive to the left-right organizer anterior fluid mechanics rather than to the nature of its fluid content.

Using a cross-species phenotypic drug discovery pipeline, compounds promoting rod photoreceptor survival in zebrafish and mouse models of retinitis pigmentosa were identified, evidence of additive effects of paired compounds and inhibition of PARP-dependent cell death suggest novel therapeutic strategies.