Berit Siedentop, Viacheslav N Kachalov ... Sebastian Bonhoeffer
A systematic review shows no evidence of harm or benefit of antibiotic combinations on resistance evolution as clinical data lack statistical power to draw definitive conclusions, highlighting a knowledge gap.
Developmental specialization of vomeronasal sensory neurons involves selective upregulation of endoplasmic reticulum genes in a subset of neurons along with a hypertrophic gyroid membrane architecture.
Associative plasticity of proximal and distal granule cell inputs to Purkinje cells enables time dependent association of information from local and distant receptive fields.
Increasing semantic relationships with old information accelerates learning and enhances memory for new information and increases the likelihood of both old and new information being recalled together.
A deep learning-based system objectively and reliably scores the Rey–Osterrieth complex figure test, enhancing the assessment of visual memory deficits from hand-drawn images in clinical settings.
A member of the Inhibitor of DNA-binding (Id) gene family, best known as negative regulators of tissue-specific master regulatory bHLH transcription factors, also suppresses non-apoptotic caspase activities.
Rebecca Warfvinge, Linda Geironson Ulfsson ... Göran Karlsson
Single-cell analysis of CML patients bone marrow at diagnosis reveals coexistence of CD26-CD35+ healthy stem cells and CD26+CD35- CML stem cells, and how the ratio between these impacts TKI response.
Miguel Martinez-Ara, Federico Comoglio, Bas van Steensel
A high-throughput enhancer-enhancer-promoter reporter assay indicates that pairs of enhancers generally activate promoters in a near-additive manner, and that promoters transform their collective effect non-linearly.
