2,126 results found
    1. Neuroscience

    Understanding neural signals of post-decisional performance monitoring: An integrative review

    Kobe Desender, K Richard Ridderinkhof, Peter R Murphy
    A computationally explicit framework can explain post-decisional neural signals of performance monitoring.
    1. Neuroscience

    Distinct temporal difference error signals in dopamine axons in three regions of the striatum in a decision-making task

    Iku Tsutsui-Kimura, Hideyuki Matsumoto ... Mitsuko Watabe-Uchida
    Dopamine signals in the ventral, dorsomedial, and dorsolateral striatum are modulated by various variables, such as stimulus-associated value, choice, confidence, but these modulations can be inclusively explained by TD errors.
    1. Neuroscience

    Neural evidence accumulation persists after choice to inform metacognitive judgments

    Peter R Murphy, Ian H Robertson ... Redmond G O'Connell
    Error detection is contingent on the continuation of evidence accumulation after choice commitment, and the speed and accuracy of this process are modulated by high-level signals from medial frontal cortex.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    BubR1 alterations that reinforce mitotic surveillance act against aneuploidy and cancer

    Robbyn L Weaver, Jazeel F Limzerwala ... Jan M van Deursen
    Strengthening of spindle assembly checkpoint activity and attachment error correction through BubR1 manipulation preserves genomic integrity and protects against tumor formation.
    1. Microbiology and Infectious Disease

    High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy

    Claudia A Vera-Arias, Aurel Holzschuh ... Cristian Koepfli
    A novel high-throughput method for Plasmodium falciparum genotyping will enable malaria control programs to make informed decisions about the best tool to use for the diagnosis of malaria.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Role of D-aminoacyl-tRNA deacylase beyond chiral proofreading as a cellular defense against glycine mischarging by AlaRS

    Komal Ishwar Pawar, Katta Suma ... Rajan Sankaranarayanan
    Along with preventing D-amino acids from being incorporated into proteins, D-aminoacyl-tRNA deacylase clears achiral glycine that is incorrectly attached to tRNAAla.
    1. Neuroscience

    Cerebellar learning using perturbations

    Guy Bouvier, Johnatan Aljadeff ... Boris Barbour
    A proposal for a complete cellular/network implementation of trial-and-error motor learning in the olivo-cerebellar system.
    1. Neuroscience

    The role of premature evidence accumulation in making difficult perceptual decisions under temporal uncertainty

    Ciara A Devine, Christine Gaffney ... Redmond G O'Connell
    Temporal uncertainty interferes with the timely onset of evidence accumulation in perceptual decision making prompting the brain to rely instead on statistical regularities in the temporal structure of the environment.
    1. Neuroscience

    Neuronal representation of saccadic error in macaque posterior parietal cortex (PPC)

    Yang Zhou, Yining Liu ... Mingsha Zhang
    Neurons in the macaque posterior parietal cortex behave like an error detector that computes the saccadic error by comparing the intended and the actual saccade end-position signals.
    1. Neuroscience

    Prediction error and repetition suppression have distinct effects on neural representations of visual information

    Matthew F Tang, Cooper A Smout ... Jason B Mattingley
    Multivariate analyses of human electrophysiological recordings revealed that the brain represents unexpected visual stimuli with greater fidelity than expected stimuli which arose independently of simple habituation arising from repetition.

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