761 results found
    1. Epidemiology and Global Health
    2. Medicine

    External validation of a mobile clinical decision support system for diarrhea etiology prediction in children: A multicenter study in Bangladesh and Mali

    Stephanie Chow Garbern, Eric J Nelson ... Daniel T Leung
    A smartphone app incorporating clinical prediction models using patient-specific and location-specific data sources in a modular approach could predict viral-only etiology of diarrhea in children under five in Bangladesh and Mali.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Point of View: Hypothesis, analysis and synthesis, it's all Greek to me

    Ioannis Iliopoulos, Sophia Ananiadou ... Vasilis J Promponas
    Many scientific terms have been borrowed from ancient languages, but their modern usage often overlooks their etymology, as do many new terms coined by scientists.
    1. Epidemiology and Global Health
    2. Medicine

    Seasonal variation and etiologic inferences of childhood pneumonia and diarrhea mortality in India

    Daniel S Farrar, Shally Awasthi ... Prabhat Jha
    Nationally-representative verbal autopsies can be linked to seasonal patterns, clinical syndromes, and climate regions to describe novel insights regarding the microbiologic etiologies of childhood pneumonia and diarrhea in India.
    1. Epidemiology and Global Health

    A modular approach to integrating multiple data sources into real-time clinical prediction for pediatric diarrhea

    Ben J Brintz, Benjamin Haaland ... Daniel T Leung
    Using a modular approach to integrate multiple data sources for the prediction of diarrhea etiology has the potential to reduce inappropriate antibiotics prescription in low-resource settings.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Derivation and external validation of clinical prediction rules identifying children at risk of linear growth faltering

    Sharia M Ahmed, Ben J Brintz ... Daniel T Leung
    Clinical prediction rules could help identify children at risk of slowed growth after an episode of diarrheal illness, and these rules may be generalizable to all children, regardless of diarrhea status.
    1. Neuroscience

    Comprehensive machine learning analysis of Hydra behavior reveals a stable basal behavioral repertoire

    Shuting Han, Ekaterina Taralova ... Rafael Yuste
    A novel automated behavior analysis method for Hydra identifies pre-defined and new behavior types, and reveals a stable behavior repertoire.
    1. Developmental Biology

    Dysregulation of sonic hedgehog signaling causes hearing loss in ciliopathy mouse models

    Kyeong-Hye Moon, Ji-Hyun Ma ... Jinwoong Bok
    Developmental defects of the cochlea caused by dysregulation of sonic hedgehog signaling are the potential etiology for hearing loss in a group of ciliopathies with defective ciliogenesis.
    1. Epidemiology and Global Health

    Identifying Plasmodium falciparum transmission patterns through parasite prevalence and entomological inoculation rate

    Benjamin Amoah, Robert S McCann ... Emanuele Giorgi
    Estimating fine-scale spatiotemporal patterns of Plasmodium falciparum transmission showed an association between entomological inoculation rate and parasite prevalence that emphasizes the value of both measures in malaria surveillance.
    1. Cell Biology

    Hypersensitive intercellular responses of endometrial stromal cells drive invasion in endometriosis

    Chun-Wei Chen, Jeffery B Chavez ... Bruce J Nicholson
    A unique functional comparison of the major endometrial cell types from 44 control and endometriosis patients demonstrates not only a uterine origin of the disease, but also that endometrial to mesothelial cell gap junctions are required for invasive lesion formation.
    1. Cell Biology
    2. Developmental Biology

    LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome

    Laura Bozal-Basterra, María Gonzalez-Santamarta ... Rosa Barrio
    LUZP1 is required for proper cilia and cytoskeleton formation.

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