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    1. Neuroscience

    A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice

    Lotfi Ferhat, Rabia Soussi ... Michel Khrestchatisky
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Neural circuit mechanisms for steering control in walking Drosophila

    Aleksandr Rayshubskiy, Stephen L Holtz ... Rachel I Wilson
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    Hexokinase regulates Mondo-mediated longevity via the PPP and organellar dynamics

    Raymond Laboy, Marjana Ndoci ... Adam Antebi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cancer Biology

    Molecular consequences of acute versus chronic CDK12 loss in prostate carcinoma nominates distinct therapeutic strategies

    Sander Frank, Thomas Persse ... Peter S Nelson
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    A comprehensive neuroanatomical survey of the Drosophila Lobula Plate Tangential Neurons with predictions for their optic flow sensitivity

    Arthur Zhao, Aljoscha Nern ... Michael B. Reiser
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Age-related changes in “cortical” 1/f dynamics are linked to cardiac activity

    Fabian Schmidt, Sarah K Danböck ... Nathan Weisz
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca2+-dependent priming

    Bassam Tawfik, Joana S Martins ... Jakob Balslev Sørensen
    Synaptotagmin-7 acts synergistically with synaptotagmin-1 by placing vesicles close to the plasma membrane within reach of the SNARE/Munc13-complex, supporting their priming and setting the stage for fast and slow fusion.
    1. Cell Biology
    2. Developmental Biology

    Cell volume changes contribute to epithelial morphogenesis in zebrafish Kupffer’s vesicle

    Agnik Dasgupta, Matthias Merkel ... Jeffrey D Amack
    During Kupffer's vesicle morphogenesis, cell volume anisotropy impacts cell shape changes.
    1. Neuroscience

    Dendritic nonlinearities are tuned for efficient spike-based computations in cortical circuits

    Balázs B Ujfalussy, Judit K Makara ... Máté Lengyel
    Dendrites combine the inputs that they receive from other neurons using calculations that have been optimized for those particular input patterns.
    1. Immunology and Inflammation

    B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size

    Sung Hoon Cho, Marissa A Jones ... Mark R Boothby
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
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