Experimental evolution shows that when selection acts on two traits constrained by a trade-off, the direction of phenotypic evolution depends on the environment.

An experimentally supported model of grid cells naturally enables them to participate in firing sequences that encode rapid trajectories in space.

Contractility wins over the polarity pathway in a tug-of-war to position a cytokinesis-like actomyosin ring at the equator of notochord cells.

Horizon scanning has been used to identify opportunities and risks presented by 20 emerging issues in the field of biological engineering.

A previously undetected dynamic cell structure orients the mitotic spindle of germ stem cells and grows over one daughter cell, thus helping to balance niche retention with niche exit.

Humans are biased in their assessment of sensory information by their own preceding categorical judgment in an attempt to remain self-consistent.

Fruit fly chromosomes are divided into discrete structural domains by regions of decompacted chromatin, suggesting a novel model for the formation of a known class of genetic elements.

There is a strand-based evolutionary mechanism for the diversification of outer membrane proteins, which has implications for how repeat proteins are created and for how outer membrane proteins fold.

Promoter interactome maps in human embryonic stem cells (ESCs) and ESC-derived early neuroectodermal progenitors link distal enhancers to putative target genes, reveal lineage-specific cis-regulatory architecture and shed light on the logic of gene regulation by multiple enhancers.

A high-throughput behavioral paradigm and computational modeling are used to decompose olfactory navigation in walking Drosophila melanogaster into a set of quantitative relationships between sensory input and motor output.