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    1. Neuroscience

    A Myelin Map of Trunk Folds in the Elephant Trigeminal Nucleus

    Noémie Reveyaz, Undine Schneeweiß ... Michael Brecht
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Condensation of LINE-1 is critical for retrotransposition

    Srinjoy Sil, Sarah Keegan ... Liam J Holt
    The LINE-1 retrotransposon protein, ORF1p, forms a condensate on RNA that is essential for retrotransposition, and may explain cis-preference through a co-translational assembly mechanism.
    1. Neuroscience

    Mechanical activation of TWIK-related potassium channel by nanoscopic movement and rapid second messenger signaling

    E Nicholas Petersen, Mahmud Arif Pavel ... Scott B Hansen
    Cells utilize a membrane-mediated mechanism for mechanosensation, which involves the disruption of lipid rafts and a signal relayed to an ion channel.
    1. Cell Biology
    2. Developmental Biology

    In vivo dynamics of skeletal muscle Dystrophin in zebrafish embryos revealed by improved FRAP analysis

    Fernanda Bajanca, Vinicio Gonzalez-Perez ... Simon M Hughes
    A multidisciplinary approach was used to translate the mathematical analysis of Dystrophin movements inside muscle cells into the biology of how Dystrophin interacts with the cell membrane.
    1. Physics of Living Systems

    Full assembly of HIV-1 particles requires assistance of the membrane curvature factor IRSp53

    Kaushik Inamdar, Feng-Ching Tsai ... Delphine Muriaux
    The formation of HIV-1 particles requires a bending of the membrane that cannot be achieved by the Gag protein alone and thus there is need for the I-BAR protein IRSp53 to aid in the formation of HIV-1 buds.
    1. Neuroscience

    The nematode worm C. elegans chooses between bacterial foods as if maximizing economic utility

    Abraham Katzen, Hui-Kuan Chung ... Shawn R Lockery
    A worm with a nervous system of only 302 neurons satisfies the necessary and sufficient conditions for value-based decision making.
    1. Neuroscience

    Neural assemblies uncovered by generative modeling explain whole-brain activity statistics and reflect structural connectivity

    Thijs L van der Plas, Jérôme Tubiana ... Georges Debrégeas
    A data-driven network model offers an interpretable and physiologically sound description of the whole-brain spontaneous neural activity of zebrafish larvae.
    1. Neuroscience

    Hierarchical temporal prediction captures motion processing along the visual pathway

    Yosef Singer, Luke Taylor ... Nicol S Harper
    Neural network modeling shows that hierarchical application of the simple computational principle of predicting future sensory input from its past can capture features of visual motion processing from the retina to the visual cortex.
    1. Neuroscience

    The unique synaptic circuitry of specialized olfactory glomeruli in Drosophila melanogaster

    Lydia Gruber, Rafael Cantera ... Jürgen Rybak
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Physics of Living Systems

    Fragmentation and aggregation of cyanobacterial colonies

    Yuri Z Sinzato, Robert Uittenbogaard ... Maziyar Jalaal
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid