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Page 3 of 142
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Uncoupling evolutionary changes in DNA sequence, transcription factor occupancy and enhancer activity

    Pierre Khoueiry, Charles Girardot ... Eileen EM Furlong
    Interspecies comparison of transcription factor occupancy during embryogenesis reveals potential co-operative relationships between factors and uncovers the inherent plasticity of developmental enhancers to overcome divergence in transcription factor occupancy.
    1. Evolutionary Biology

    Adaptation dynamics between copy-number and point mutations

    Isabella Tomanek, Călin C Guet
    In bacteria, frequent adaptive copy-number mutations can hinder the fixation of beneficial point mutations and hence the divergence of duplicated DNA sequences.
    1. Evolutionary Biology
    2. Neuroscience

    Mushroom body evolution demonstrates homology and divergence across Pancrustacea

    Nicholas James Strausfeld, Gabriella Hanna Wolff, Marcel Ethan Sayre
    Demonstrating extreme diversity across crustaceans while contrasting with evolutionary stability in insects, mushroom body homologues further underpin the unity of Pancrustacea and shed new light on arthropod brain evolution.
    1. Developmental Biology
    2. Evolutionary Biology

    Conservation of peripheral nervous system formation mechanisms in divergent ascidian embryos

    Joshua F Coulcher, Agnès Roure ... Sébastien Darras
    Developmental regulatory mechanisms for peripheral nervous system formation appear to be conserved in ascidians despite extensive genomic divergence after 390 MY of separate evolution.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    High rates of evolution preceded shifts to sex-biased gene expression in Leucadendron, the most sexually dimorphic angiosperms

    Mathias Scharmann, Anthony G Rebelo, John R Pannell
    In the dioecious plant genus Leucadendron, shifts to sex-biased gene expression occurred predominantly in genes with ancestrally high rates of expression evolution, and were not correlated with morphology.
    1. Evolutionary Biology

    An estimate of the deepest branches of the tree of life from ancient vertically evolving genes

    Edmund RR Moody, Tara A Mahendrarajah ... Tom A Williams
    Relatively few genes have evolved vertically from the last universal common ancestor to modern prokaryotes, and phylogenetic analysis of these genes demonstrates a great genetic distance between Archaea and Bacteria.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates

    Hannah K Long, David Sims ... Robert J Klose
    Islands of non-methylated DNA are shown to perform a similar epigenetic role in many different vertebrate species.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Evolution of host-microbe cell adherence by receptor domain shuffling

    EmilyClare P Baker, Ryan Sayegh ... Matthew F Barber
    Rapid evolution and gene conversion of a primate cell surface receptor family blocks recognition by pathogenic bacteria.
    1. Ecology
    2. Evolutionary Biology

    The deep-rooted origin of disulfide-rich spider venom toxins

    Naeem Yusuf Shaikh, Kartik Sunagar
    A remarkable case of the common evolutionary origin of a prominent spider venom component.
    1. Evolutionary Biology
    2. Neuroscience

    Shore crabs reveal novel evolutionary attributes of the mushroom body

    Nicholas Strausfeld, Marcel E Sayre
    Dramatic phenotypic divergence of crustacean mushroom bodies map to phylogenetic lineages, thereby offering unexplored opportunities for relating divergent cognitive centers to different ecologies and behavioral repertoires required to negotiate them.