3,485 results found
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices

    Eitan Lerner, Anders Barth ... Shimon Weiss
    A summary of the current “state-of-the-field” of single-molecule FRET used for probing biomolecular structural dynamics.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural insights into actin isoforms

    Amandeep S Arora, Hsiang-Ling Huang ... Krishna Chinthalapudi
    The functional differences between actin isoforms have been explored through structural studies.
    1. Neuroscience

    Hierarchical temporal prediction captures motion processing along the visual pathway

    Yosef Singer, Luke Taylor ... Nicol S Harper
    Neural network modeling shows that hierarchical application of the simple computational principle of predicting future sensory input from its past can capture features of visual motion processing from the retina to the visual cortex.
    1. Chromosomes and Gene Expression

    What AlphaFold tells us about cohesin’s retention on and release from chromosomes

    Kim A Nasmyth, Byung-Gil Lee ... Jan Löwe
    Structural predictions using AlphaFold suggest a mechanism by which Wapl mediates cohesin's dissociation from chromatin, a process whose downregulation is essential for VDJ recombination and diverse protocadherin gene expression.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling

    Nicolas Aznar, Krishna K Midde ... Pradipta Ghosh
    Daple is a guanine nucleotide-exchange factor (GEF) for trimeric G proteins that enables Wnt/Frizzled receptors to transactivate G proteins during non-canonical Wnt signaling.
    1. Neuroscience

    Connectomics of the Octopus vulgaris vertical lobe provides insight into conserved and novel principles of a memory acquisition network

    Flavie Bidel, Yaron Meirovitch ... Binyamin Hochner
    Connectomics of the octopus 'fan-out fan-in’ learning network reveals that the intermediate layer uses approximately 22×106 excitatory interneurons, each can store a single sensory input, while approximately 400×103 integrating inhibitory interneurons adjust the network output level.
    1. Ecology

    A beta-glucosidase of an insect herbivore determines both toxicity and deterrence of a dandelion defense metabolite

    Meret Huber, Thomas Roder ... Matthias Erb
    An insect digestive enzyme metabolizes a plant defense compound and thereby modulates herbivore performance and host plant choice, which in turn may alter plant defense evolution in nature.
    1. Neuroscience

    Ca2+ entry through NaV channels generates submillisecond axonal Ca2+ signaling

    Naomi AK Hanemaaijer, Marko A Popovic ... Maarten HP Kole
    High-speed calcium imaging from the axon initial segment shows that sodium channels are in part permeable to calcium ions.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Comparative interactome analysis of α-arrestin families in human and Drosophila

    Kyung-Tae Lee, Inez KA Pranoto ... Jin-Wu Nam
    Unveiling the high-confidence protein–protein interaction networks of human and fly α-arrestins provides insights into conserved and species-specific functional roles depending on their protein domains and motifs.
    1. Ecology
    2. Plant Biology

    Plant defense phenotypes determine the consequences of volatile emission for individuals and neighbors

    Meredith C Schuman, Silke Allmann, Ian T Baldwin
    Both the frequency of sesquiterpene-emitting individuals and the defense capacity of individual plants determine the consequences of sesquiterpene volatile emission for individuals and their neighbors in populations of the wild tobacco Nicotiana attenuata.

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