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    1. Immunology and Inflammation

    Resting natural killer cells promote the progress of colon cancer liver metastasis by elevating tumor-derived stem cell factor

    Chenchen Mao, Yanyu Chen ... Xiangyang Xue
    Resting natural killer cells promote the progress of colon cancer liver metastasis (CCLM), which may be exploited for novel strategies to improve therapeutic outcomes for patients with CCLM.
    1. Ecology

    Full factorial construction of synthetic microbial communities

    Juan Diaz-Colunga, Pablo Catalan ... Alvaro Sanchez
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Evolutionary Biology
    2. Immunology and Inflammation

    An arms race between 5’ppp-RNA virus and its alternative recognition receptor MDA5 in RIG-I-lost teleost fish

    Shang Geng, Xing Lv ... Tianjun Xu
    5’ppp-RNA, a traditional ligand for RIG-I, can be recognized by MDA5 in species such as Miichthys miiuy and Gallus gallus that lack RIG-I.
    1. Biochemistry and Chemical Biology

    Stabilization of GTSE1 by cyclin D1-CDK4/6 promotes cell proliferation: relevance in cancer prognosis

    Nelson García-Vázquez, Tania J González-Robles ... Sharon Kaisari
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

    Joshua G Medina-Feliciano, Griselle Valentín-Tirado ... José E García-Arrarás
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Computational and Systems Biology
    2. Cancer Biology

    Computational Engineering of a Therapeutic Antibody to Inhibit Multiple Mutants of HER2 Without Compromising Inhibition of the Canonical HER2

    Sapir Peled, Julia Guez-Haddad ... Yanay Ofran
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology
    2. Computational and Systems Biology

    circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA

    Trine Line Hauge Okholm, Andreas Bjerregaard Kamstrup ... Christian Kroun Damgaard
    A dysregulated circular RNA in bladder cancer controls oncogenic pathways by tethering specific RNA-binding proteins, which in turn inhibits their normal functions.
    1. Microbiology and Infectious Disease
    2. Evolutionary Biology

    The Mycobacterium tuberculosis complex pangenome is small and driven by sub-lineage-specific regions of difference

    Mahboobeh Behruznia, Maximillian Marin ... Conor J Meehan
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Inadequate
    1. Cell Biology
    2. Genetics and Genomics

    SCC3 is an axial element essential for homologous chromosome pairing and synapsis

    Yangzi Zhao, Lijun Ren ... Zhukuan Cheng
    SCC3 not only functions as a member of cohesin complex but also participates in homologous pairing and synapsis during rice meiosis.
    1. Medicine
    2. Microbiology and Infectious Disease

    Neuroinfectiology of an atypical anthrax-causing pathogen in wild chimpanzees

    Tobias Gräßle, Carsten Jäger ... Markus Morawski
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
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