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If released in the wild, current CRISPR-based gene drive systems designed to alter populations could spread much farther than intended, despite the evolution of drive resistance.

Empathy can evolve and foster cooperation in a game-theoretic analysis of behavior.

The transcription factor HAND2 evolved uterine expression during the origins of pregnancy and may be important for maternal-fetal immune signaling and parturition.

A computational model shows that natural selection can cause populations to evolve a distinctive population-level phenotype: the ability to transition between collective states in response to the environment.

In an in vitro RNA replication system, an RNA spontaneously diversifies and continuously evolves through coevolution with parasitic entities.

5’ppp-RNA, a traditional ligand for RIG-I, can be recognized by MDA5 in species such as Miichthys miiuy and Gallus gallus that lack RIG-I.

Environmental heterogeneity can dramatically reduce the efficacy of selection and alter the neutral evolutionary dynamics in microbial range expansions.

Bats' uniquely robust innate antiviral immune defenses select for faster transmitting viruses likely to generate extreme virulence upon spillover to secondary hosts with immune systems divergent from those of bat.

Selection bias, also known as collider bias, likely explains the apparent protective effect of G6PD deficiency against cerebral falciparum malaria.

Apicomplexan-like parasites originated several times independently and many of them contain cryptic plastid organelles, which demonstrate that the parasites evolved from photosynthetic algae.