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Limb Development: A lesson in homology
The same genes and signaling pathways control the formation of limbs in vertebrates, arthropods and cuttlefish.
Genetics and Genomics
Brain Size: Gene losses did not stop the evolution of big brains
Cristian Cañestro, Vittoria Roncalli
Elephants and fruit bats have evolved large brains even though they have lost a gene that is fundamental to the supply of energy to the brain when glucose is not available.
Learning: The cerebellum influences vocal timing
We are starting to understand how the cerebellum contributes to vocal learning in songbirds.
Genetics and Genomics
Neutral Evolution: The randomness that shapes our DNA
Just 5% of the human genome is subject to neutral evolution but this process remains central to understanding the history of human migration across the Earth.
Biochemistry and Chemical Biology
Intracellular Diffusion: How bacteria keep proteins moving
Conrad W Mullineaux
Bacteria contain large numbers of negatively-charged proteins to avoid the electrostatic interactions with ribosomes that would dramatically reduce protein diffusion.
Multicellularity: The evolution of gene regulation
Veronica Hinman, Gregory Cary
The gene regulation mechanisms necessary for the development of complex multicellular animals have been found in sponges.
Research: Publication bias and the canonization of false facts
Silas Boye Nissen et al.
Publication bias, in which positive results are preferentially reported by authors and published by journals, can restrict the visibility of evidence against false claims and allow such claims to be canonized inappropriately as facts.
Computational and Systems Biology
Adaptive Evolution: At the mercy of viruses
Claus O Wilke, Sara L Sawyer
The Natural History of Model Organisms: An organismal perspective on
development, origins and diversification
Matthew J Kourakis, William C Smith
The life cycle and morphology of the sea squirt
shed light on vertebrate evolution.
The Natural History of Model Organisms: Planting molecular functions in an ecological context with
Research in molecular ecology and evolution is increasingly utilizing the model plant Arabidopsis thaliana, placing a spotlight on its natural history.
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