2,600 results found
    1. Cell Biology

    An adaptation of astronomical image processing enables characterization and functional 3D mapping of individual sites of excitation-contraction coupling in rat cardiac muscle

    Qinghai Tian et al.
    The fusion of astronomy and cellular cardiology reveals the 3D arrangement and the firing reliability of active excitation-contraction coupling sites in beating cardiac myocytes.
    1. Neuroscience

    Sensory experience inversely regulates feedforward and feedback excitation-inhibition ratio in rodent visual cortex

    Nathaniel J Miska et al.
    Sensory deprivation suppresses cortical responsiveness through a selective remodeling of excitatory and inhibitory microcircuit motifs, by simultaneously amplifying feedforward and suppressing feedback excitation.
    1. Neuroscience
    2. Medicine

    Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

    Stavros Trakoshis et al.
    Excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic males versus females.
    1. Medicine
    2. Neuroscience

    Autism: Balancing excitation and inhibition in the autistic brain

    Charlotte M Pretzsch, Dorothea L Floris
    A metric called the Hurst exponent could be a useful biomarker for studies exploring brain differences between men and women with autism spectrum disorder.
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  1. Meta-Research: Gender variations in citation distributions in medicine are very small and due to self-citation and journal prestige

    Jens Peter Andersen et al.
    In studies of gender disparities in academia, increased focus is required on within-group variability and between-group overlap of distributions when interpreting and reporting results.
    1. Neuroscience

    The functional organization of excitation and inhibition in the dendrites of mouse direction-selective ganglion cells

    Varsha Jain et al.
    Accurate direction-selective information is present within small sections of the dendrites, raising the possibility that single dendrites utilize parallel processing schemes to process motion information.
    1. Neuroscience

    C1 neurons are part of the circuitry that recruits active expiration in response to the activation of peripheral chemoreceptors

    Milene R Malheiros-Lima et al.
    An unbiased description reveals potential implications for understanding the developmental mechanisms that match respiratory supply and demand during hypoxia.
    1. Neuroscience

    Precise excitation-inhibition balance controls gain and timing in the hippocampus

    Aanchal Bhatia et al.
    Delayed inhibition precisely balances excitation from arbitrary combinations of CA3 neurons and controls the gain of CA1 output by reducing inhibitory delay with increasing excitation.
    1. Neuroscience

    Beyond excitation/inhibition imbalance in multidimensional models of neural circuit changes in brain disorders

    Cian O'Donnell et al.
    Computational modeling and analysis of mouse neural population data finds that the excitation/inhibition imbalance theory of brain disorders is too limited to account for key changes in neural activity statistics.
    1. Neuroscience

    Cellular resolution circuit mapping with temporal-focused excitation of soma-targeted channelrhodopsin

    Christopher A Baker et al.
    Combining spatial restriction of channelrhodopsin to the neuronal cell body with two photon excitation and calcium imaging will enable production of high resolution maps of neural circuitry.

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