Distinct brain states govern resting state functional architecture revealed by neurophysiologically defined simultaneous optic-fiber-based calcium recordings and task-free functional magnetic resonance imaging (fMRI) in rats.
The PreBötzinger complex, which contains neurons that are the kernel for inspiratory rhythm generation, also contains sympathoexcitatory and parasympathoinhibitory neurons that drive respiratory-phase oscillations in blood pressure and heart rate.
A new collection of fly strains comprehensively targets the motor neurons of the proboscis, allowing separate control of every muscle to determine how this appendage achieves flexible, directed reaching.
Calcium-driven protein changes, causing glycogenolysis, poor synthesis, and diminished content of glycogen, along with diminished glucose transporters, lead to hyperglycemia in patients prone to calcium leaks from intracellular muscle stores.
Identification and functional characterization of the first non-chordate kisspeptin neuropeptide system in the sea cucumber indicates the ancient origin of the intracellular signaling and physiological functions of this molecular system.
Disease-associated mutants of the TRPM3 ion channel are overactive, and they are inhibited by the antiepileptic medication primidone, offering a potential therapeutic intervention to treat this channelopathy.