1,497 results found
    1. Neuroscience

    Sensory experience inversely regulates feedforward and feedback excitation-inhibition ratio in rodent visual cortex

    Nathaniel J Miska et al.
    Sensory deprivation suppresses cortical responsiveness through a selective remodeling of excitatory and inhibitory microcircuit motifs, by simultaneously amplifying feedforward and suppressing feedback excitation.
    1. Neuroscience

    Distinct hierarchical alterations of intrinsic neural timescales account for different manifestations of psychosis

    Kenneth Wengler et al.
    fMRI evidence for distinct hierarchical alterations in intrinsic neural timescales for different positive symptoms of schizophrenia support hierarchical perceptual-inference models of psychosis and suggest local increases in excitation-inhibition ratio.
    1. Neuroscience

    Precise excitation-inhibition balance controls gain and timing in the hippocampus

    Aanchal Bhatia et al.
    Delayed inhibition precisely balances excitation from arbitrary combinations of CA3 neurons and controls the gain of CA1 output by reducing inhibitory delay with increasing excitation.
    1. Neuroscience
    2. Medicine

    Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

    Stavros Trakoshis et al.
    Excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic males versus females.
    1. Neuroscience

    Probing the functional impact of sub-retinal prosthesis

    Sébastien Roux et al.
    Existing artificial retinas produce distorted and imprecise activation of the visual system, but reverse engineering promises to refine the induced activation patterns.
    1. Cell Biology
    2. Neuroscience

    Multiple factors maintain assembled trans-SNARE complexes in the presence of NSF and αSNAP

    Eric A Prinslow et al.
    Biophysical analyses indicate that Munc18-1, Munc13-1, synaptotagmin-1 and complexin-1 maintain assembled trans-SNARE complexes in the presence of NSF-alphaSNAP, suggesting that they form part of the primed state of synaptic vesicles.
    1. Neuroscience

    A transformation from temporal to ensemble coding in a model of piriform cortex

    Merav Stern et al.
    A spiking network model that examines the transformation of odor information from olfactory bulb to piriform cortex demonstrates how intrinsic cortical circuitry preserves representations of odor identity across odorant concentrations.
    1. Neuroscience
    2. Physics of Living Systems

    A geometric attractor mechanism for self-organization of entorhinal grid modules

    Louis Kang, Vijay Balasubramanian
    The hierarchy of entorhinal grid cell modules with constant scale ratios can self-organize through a new geometrically organized attractor mechanism.
    1. Neuroscience

    Irregular spiking of pyramidal neurons organizes as scale-invariant neuronal avalanches in the awake state

    Timothy Bellay et al.
    Spontaneous, irregular spiking in single cortical pyramidal neurons assembles as neuronal avalanches at the group level identifying a robust scale-invariant organization of resting activity in the awake state.
    1. Neuroscience

    Two opposite voltage-dependent currents control the unusual early development pattern of embryonic Renshaw cell electrical activity

    Juliette Boeri et al.
    A simple mechanism, based on the synergy of two major opposing voltage-dependent currents that are ubiquitous in neurons, produces functional diversity of developing Renshaw cells in the embryo.

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