906 results found
    1. Chromosomes and Gene Expression

    Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins

    Haiyang Zhang et al.
    Establishment of replication-timing involves Fkh1-dependent recruitment and execution of DDK function in G1 phase resulting in dynamic relocalization of origins within the nucleus in anticipation of CDK-dependent origin activation.
    1. Human Biology and Medicine
    2. Neuroscience

    High-intensity training enhances executive function in children in a randomized, placebo-controlled trial

    David Moreau et al.
    Short bursts of high-intensity exercise elicit robust improvements in core cognitive abilities, especially in individuals whose genotype is associated with lower cognitive performance.
    1. Neuroscience

    Recruitment of the default mode network during a demanding act of executive control

    Ben M Crittenden et al.
    The default mode network in the brain is activated during the performance of executive-type tasks when a substantial change in cognitive contents is required.
    1. Developmental Biology

    A branched heterochronic pathway directs juvenile-to-adult transition through two LIN-29 isoforms

    Chiara Azzi et al.
    Distinct regulation endows two isoforms of the transcription factor LIN-29 with distinct functions to achieve coordinated execution of separate juvenile-to-adult transition events in Caenorhabditis elegans..
    1. Cancer Biology
    2. Cell Biology

    Cyclin Kinase-independent role of p21CDKN1A in the promotion of nascent DNA elongation in unstressed cells

    Sabrina F Mansilla et al.
    A new tumor suppressor function of p21, needed at each undamaged duplication cycle, ensures the adequate execution of the DNA replication program thereby protecting the genome integrity.
    1. Neuroscience

    The hierarchical organization of the lateral prefrontal cortex

    Derek Evan Nee, Mark D'Esposito
    Areas in the middle of the lateral prefrontal cortex select behaviors by taking into account both current and future needs.
    1. Human Biology and Medicine

    Point of View: Competency-based assessment for the training of PhD students and early-career scientists

    Michael F Verderame et al.
    A method to assess the training of scientists, based on a set of 10 core competencies, is proposed.
    1. Stem Cells and Regenerative Medicine

    Cutting Edge: Promoting international collaboration and creativity in doctoral students

    Christopher M Groen et al.
    Staff from the Mayo Clinic in the US and the Karolinska Institute in Sweden describe a joint transatlantic course intended to broaden the horizons of the next generation of researchers in the field of regenerative medicine.
    1. Neuroscience

    Neuroscience: Watching the brain in action

    Bradford Z Mahon
    Insight
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