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Transcription factors can read out both the sequence and the structure of the non-template DNA strand in the transcription bubble, expanding the repertoire of mechanisms to control transcription.

A comprehensive resource to systematically evaluate the genetically predicted associations between 125 polygenic risk scores and 249 metabolic traits.

The present findings reveal that subjectively perceived similarities between objects, including those unique to individual observers, are reflected with highest fidelity at the apex of the ventral visual pathway in the medial temporal lobe.

Combining 7 Tesla fMRI and MEG data collected during a challenging visual recognition task revealed distinct neural representational formats in ventral visual and frontoparietal regions, and the emergence of recognition-related signals prior to category-related information.

Distinct computational levels of uncertainty compel agents to gain information about hidden states in the world (‘active inference’) or optimise their ‘world model’ as such (‘active learning’).

An automatic computer vision analysis approach can assist in the diagnosis of rare genetic disorders by using ordinary photographs of patients.

Targeted recruitment of protein kinase A subunits enables distinctive regulation of the functional expression of a potassium channel depending on whether the enzyme is targeted to a pore-forming or auxiliary subunit.

Integrating human embryonic transcriptomes from 15 sites during organogenesis identifies novel expression signatures linked to congenital disorders and a new programme of non-coding gene expression.

Mobile phone data reveal aspects of human mobility patterns in Sub-Saharan Africa missed by standard spatial models however, model estimates can be improved by accounting for trip urbanicity and region.

The sequence of neural and physiological processes underlying action-stopping has been delineated.