Gradual downregulation of each of the subunits of the evolutionary-conserved exocyst holocomplex shows that the complex is required for biogenesis, maturation, and exocytosis of secretory granules in Drosophila salivary glands.
Seiichi Koike, Masashi Tachikawa ... Masayuki Masu
There are two distinct modes of late endosome fusion in the mouse yolk sac visceral endoderm cells and actin dynamics plays a role in regulating vesicle fusion.
Quynh Anh Thi Nguyen, Andrea Rocha ... Sachiko Haga-Yamanaka
A molecular genetics study reveals an accessory olfactory-to-hypothalamic circuit in mice that optimizes defensive behaviors according to the imminence of predator threats.
In a mouse model of Sjogren's disease, mitochondrial function and Ca2+ signaling are disrupted resulting in altered coupling between Ca2+ release and Ca2+ activated Cl- channels and salivary gland hypofunction.
TRPV4 and ANO1 are co-expressed in the sweat glands of mouse food pads and found to be involved in perspiration, suggesting that local temperature sensation through TRPV4 could control seating.
Open-top Bessel beam two-photon light sheet microscopy have the potential for rapid and accurate nondestructive pathology by visualizing 3D histological information.
ECM-Itgb1 signaling and cell-cell adhesion are pivotal and coordinate together to regulate pancreatic islet aggregation, architecture, and functional maturation during development.
Coral symbiotic alga is capable of degrading the own cell wall components by cellulase-related enzymes and releasing sugars as a simple and autonomous environmental response, even when the host-derived signals are not present.
