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Photodamaged chloroplasts are targeted for vacuolar degradation through microautophagy by the NBR1 autophagy receptor without the participation of the canonical autophagy machinery.

A combination of animal models reveal how the molecular mechanisms of exosome secretion (RalA/B-dependent) are linked to their cargo content and their function in breast cancer pre-metastatic niche formation.

Psychosocial environments modulate genetic risk of asthma and other allergic diseases through altered peripheral blood gene expression.

The autophagosomal membrane becomes negatively charged during maturation due to the accumulation of PI4P, leading to the recruitment of syntaxin 17, which is required for autophagosome-lysosome fusion.

In Drosophila oocytes, the exclusion of the scaffold protein PAR3 from the posterior cortex depends on PAR1 and endocytosis, while its anterior localisation requires microtubules and recycling endosomes.

ARL13B regulates cell ciliation and cilia length from within cilia and Sonic hedgehog response from outside of cilia indicating the two processes can be spatially uncoupled.

Cellular etiology of a human WASH complex mutation in mice reveals its specific roles in neuronal organelle trafficking and a surprising role in motor impairments.

In cell types that acquire planar cell polarity, the protein Flattop regulates basal body docking and positioning.