34 results found
    1. Cell Biology

    A ‘torn bag mechanism’ of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes)

    Tamás Visnovitz, Dorina Lenzinger ... Edit I Buzas
    A novel 'torn bag mechanism' is described for the release of LC3 positive and negative small extracellular vesicles (exosomes) from amphiectosomes.
    Version of Record
    Short Report
    • Important
    • Compelling
    1. Microbiology and Infectious Disease

    A macroevolution-inspired approach to reveal novel antibiotic resistance mechanisms

    Fernanda Subtil, Teresa Machado ... Luiz Pedro de Carvalho
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum

    Lin Wei, Hai-Yan Cao ... Fuchuan Li
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons

    Guoqiang Wang, Ryan J Guasp ... Monica Driscoll
    Large extracellular vesicle extrusion that eliminates neuronal protein aggregates and organelles is potentiated by uterine filling, linking reproductive status to maternal nervous system health, and demonstrating mechanobiology components in exophergenesis.
    1. Biochemistry and Chemical Biology

    Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy

    Boglarka Zambo, Evelina Edelweiss ... Gergo Gogl
    The SH3 domain of BIN1 mediates an unexpectedly large array of interactions, which is perturbed by missense variants.
    1. Neuroscience

    Perceptual error based on Bayesian cue combination drives implicit motor adaptation

    Zhaoran Zhang, Huijun Wang ... Kunlin Wei
    Model based on Bayesian cue combination shows that procedural motor learning is driven by perceptual error in localizing one's effector.
    1. Neuroscience

    The archerfish uses motor adaptation in shooting to correct for changing physical conditions

    Svetlana Volotsky, Opher Donchin, Ronen Segev
    The archerfish adapts with egocentric reference frame to correct for different conditions during shot above water level.
    1. Developmental Biology

    Cytoneme-mediated intercellular signaling in keratinocytes essential for epidermal remodeling

    Yi Wang, Qingan He ... Dae Seok Eom
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Cell Biology

    Spatiotemporal dissection of the Golgi apparatus and the ER-Golgi intermediate compartment in budding yeast

    Takuro Tojima, Yasuyuki Suda ... Akihiko Nakano
    Spatiotemporal mapping of a variety of proteins in and around the Golgi apparatus in budding yeast was performed using super-resolution live imaging microscopy and identified the ER-Golgi intermediate compartment that matures into the Golgi.
    1. Neuroscience

    Proteostress: Mechanosensory neurons under pressure

    Erin Cram
    A build-up of eggs in the uterus of the nematode C. elegans triggers the release of large extracellular vesicles, called exophers, from neurons that are sensitive to mechanical forces.
    Version of Record
    Insight

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