6,423 results found
    1. Cell Biology
    2. Evolutionary Biology

    Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25

    P Richard J Yulo, Nicolas Desprat ... Heather L Hendrickson
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    High-Resolution Genome-Wide Maps Reveal Widespread Presence of Torsional Insulation

    Porter M Hall, Lauren A Mayse ... Michelle D Wang
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    Visual homogeneity computations in the brain enable solving property-based visual tasks

    Georgin Jacob, RT Pramod, SP Arun
    Seemingly disparate property-based tasks (oddball search, same-different and symmetry) are solved by computing a novel image property, visual homogeneity, which is localized to the object selective cortex.
    1. Structural Biology and Molecular Biophysics

    Wide transition-state ensemble as key component for enzyme catalysis

    Gabriel E Jara, Francesco Pontiggia ... Dorothee Kern
    Computational and experimental evidence shows that the reaction catalyzed by adenylate kinase operates through a broad transition-state ensemble (TSE), utilizing protein conformational diversity to reduce activation entropy.
    1. Cell Biology

    Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis

    Jingjing Li, Xinyue Wang ... Vincent Archambault
    Ankle2 functions as a regulatory subunit of PP2A and interacts with the endoplasmic reticulum protein Vap33 to promote the dephosphorylation of BAF as part of nuclear reassembly after mitosis.
    1. Neuroscience

    An adaptable, reusable, and light implant for chronic Neuropixels probes

    Célian Bimbard, Flóra Takács ... Philip Coen
    The Apollo implant, an open-source device tested in eight laboratories, can be used to reversibly implant Neuropixels probes and track the activity of populations of neurons across days.
    1. Neuroscience

    A deep learning framework for automated and generalized synaptic event analysis

    Philipp S O’Neill, Martín Baccino-Calace ... Igor Delvendahl
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Genomic and structural insights into Jyvaskylavirus, the first giant virus isolated from Finland

    Gabriel Magno de Freitas Almeida, Iker Arriaga ... Lotta-Riina Sundberg
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    2-oxoglutarate triggers assembly of active dodecameric Methanosarcina mazei glutamine synthetase

    Eva Herdering, Tristan Reif-Trauttmansdorff ... Ruth A Schmitz
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Human Brain-Wide Activation of Sleep Rhythms

    Haiteng Wang, Qihong Zou ... Yunzhe Liu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete

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