9,741 results found
    1. Neuroscience

    Exploring the expression patterns of palmitoylating and de-palmitoylating enzymes in the mouse brain using the curated RNA-seq database BrainPalmSeq

    Angela R Wild, Peter W Hogg ... Shernaz X Bamji
    A curated resource to study the brain RNA expression patterns of the genes that regulate palmitoylation is presented, alongside a detailed exploration of how these patterns can inform future research.
    1. Developmental Biology

    Quantification of gene expression patterns to reveal the origins of abnormal morphogenesis

    Neus Martínez-Abadías, Roger Mateu Estivill ... James Sharpe
    Quantitative analyses associating the morphology of developing organs with dynamic gene expression patterns can reveal biological phenomena that cause malformations and malfunction but remain elusive to traditional qualitative assessments.
    1. Computational and Systems Biology
    2. Chromosomes and Gene Expression

    NF-κB oscillations translate into functionally related patterns of gene expression

    Samuel Zambrano, Ilario De Toma ... Alessandra Agresti
    NF-κB oscillations synchronize to external perturbations as a damped oscillator, producing different transcription dynamics.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Unified bursting strategies in ectopic and endogenous even-skipped expression patterns

    Augusto Berrocal, Nicholas C Lammers ... Michael B Eisen
    Drosophila melanogastereven-skipped enhancers control transcriptional bursting by modulating frequency and amplitude, regardless of varying transcription factor inputs, even when mutated to express in embryonic regions not under selective pressure.
    1. Genetics and Genomics

    Expansion of the circadian transcriptome in Brassica rapa and genome-wide diversification of paralog expression patterns

    Kathleen Greenham, Ryan C Sartor ... C Robertson McClung
    Whole genome duplication in Brassica rapa is accompanied by both expansion of the circadian transcriptome and widespread temporal reconfiguration of gene regulatory networks consistent with subfunctionalization among pairs of paralogs.
    1. Computational and Systems Biology
    2. Developmental Biology

    How enhancers regulate wavelike gene expression patterns

    Christine Mau, Heike Rudolf ... Ezzat El-Sherif
    An experimental and computational system has been developed to investigate how wavelike gene expression patterns are generated during embryonic development.
    1. Neuroscience

    A searchable image resource of Drosophila GAL4 driver expression patterns with single neuron resolution

    Geoffrey W Meissner, Aljoscha Nern ... FlyLight Project Team
    Single neuron images of Drosophila driver lines reveal neuron shape and are searchable, enabling comparisons to electron microscopy and prediction of intersectional neuron targeting strategies.
    1. Developmental Biology

    Hedgehog signaling patterns the oral-aboral axis of the mandibular arch

    Jingyue Xu, Han Liu ... Rulang Jiang
    SHH signaling acts through FOXF1/2 transcription factors and antagonizes BMP signaling to specify oral fate and pattern the oral-aboral axis of the mandibular arch to ensure proper formation of jaws.
    1. Developmental Biology
    2. Neuroscience

    Low FoxO expression in Drosophila somatosensory neurons protects dendrite growth under nutrient restriction

    Amy R Poe, Yineng Xu ... Chun Han
    The development of Drosophila somatosensory neurons is spared under nutrient deficiency so that they grow more dendrites and make animals more sensitive to environmental stimuli.
    1. Developmental Biology

    The E3 ubiquitin ligase RNF220 maintains hindbrain Hox expression patterns through regulation of WDR5 stability

    Huishan Wang, Xingyan Liu ... Pengcheng Ma
    The protein stability of WDR5, the core component of TrxG complex, is controlled by the ubiquitin ligase RNF220, which involves in the maintenance of Hox patterns in mouse hindbrain.

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